https://scholars.lib.ntu.edu.tw/handle/123456789/428867
DC 欄位 | 值 | 語言 |
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dc.contributor.author | YUNN-SHIUAN LIAO | en_US |
dc.contributor.author | Lee, L. W. | en_US |
dc.contributor.author | Yang, P. H. | en_US |
dc.contributor.author | Kuo, L. M. | en_US |
dc.contributor.author | Kuan, L. Y. | en_US |
dc.contributor.author | WEN-YIH TSENG | en_US |
dc.contributor.author | Hwang, D. W. | en_US |
dc.creator | Hwang, D. W.;WEN-YIH ISAAC TSENG;Kuan, L. Y.;Kuo, L. M.;Yang, P. H.;Lee, L. W.;YUNN-SHIUAN LIAO | - |
dc.date.accessioned | 2019-10-29T08:20:29Z | - |
dc.date.available | 2019-10-29T08:20:29Z | - |
dc.date.issued | 2019-05-01 | - |
dc.identifier.issn | 00099260 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/428867 | - |
dc.description.abstract | © 2019 AIM: To determine the feasibility of semi-quantitative haemodynamic parameters derived from dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) to assess liver fibrosis. MATERIALS AND METHODS: Seventy-five patients with Child's A classification (males/females=24/51; average age, 58 years; range, 30–80 years) received DCE-MRI 3 days prior to hepatectomy. Semi-quantitative haemodynamic parameters, including the wash-in slope, wash-out slope, and time-to-peak, were calculated from DCE-MRI data. Liver fibrosis of the resected non-tumour liver was graded pathologically from F0 (no fibrosis) to F6 (cirrhosis) in the regions corresponding to those assessed by DCE-MRI. RESULTS: The wash-out slope showed higher interobserver and intra-observer reliabilities than the wash-in slope and time-to-peak. There was a significant positive correlation between the wash-out slope and pathological grade of fibrosis (Spearman's correlation coefficient: r=0.5331, p<0.0001). The area under the receiver operating characteristic curve was 0.8066 when using the wash-out slope to differentiate cirrhosis (grade F6) from non-cirrhosis (grades F0–5). Using the cut-off point that maximised specificity, the sensitivity was 62.07%, specificity was 91.30%, positive predictive value was 81.81%, negative predictive value was 79.25%, and accuracy was 80%. CONCLUSIONS: The wash-out slope derived from DCE-MRI might be potentially useful in assessing liver cirrhosis in patients with Child's A classification before hepatectomy. | en_US |
dc.relation.ispartof | Clinical Radiology | en_US |
dc.title | Assessment of liver cirrhosis for patients with Child's A classification before hepatectomy using dynamic contrast-enhanced MRI | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.crad.2019.01.017 | - |
dc.identifier.pmid | 30799098 | - |
dc.identifier.scopus | 2-s2.0-85061646960 | - |
dc.identifier.url | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061646960&doi=10.1016%2fj.crad.2019.01.017&partnerID=40&md5=1fb40f9b61a12ddc77281bcf58231e5b | - |
dc.relation.journalvolume | 74 | en_US |
dc.relation.journalissue | 5 | en_US |
dc.relation.pageend | 407.e17 | en_US |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Medical Device and Imaging | - |
crisitem.author.dept | Biomedical Engineering | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.dept | Medical Imaging-NTUH | - |
crisitem.author.orcid | 0000-0002-9005-7451 | - |
crisitem.author.orcid | 0000-0002-2314-6868 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Engineering | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫療器材與醫學影像研究所 |
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