https://scholars.lib.ntu.edu.tw/handle/123456789/429968
標題: | Pixel-wise derivation of pulmonary regurgitation index could alter clinical decision: a phase-contrast MR imaging study on patients with repaired tetralogy of Fallot | 作者: | Wu PH Chung HW Wu MT Ko CW HSIAO-WEN CHUNG |
關鍵字: | Phase contrast magnetic resonance; Pixel-wise derivation; Quantitative underestimation; Regurgitant fraction; Tetralogy of Fallot | 公開日期: | 2017 | 卷: | 93 | 起(迄)頁: | 332 | 來源出版物: | European Journal of Radiology | 摘要: | Purpose Regurgitant fraction (RF) measured from 2D phase-contrast MRI has been used as a standard to quantitate the degree of pulmonary regurgitation and serves as a determinant indicator of prognosis for tetralogy of Fallot after surgical repair. This study demonstrated the potential underestimate of RF using the conventional definition and its impact on clinical decision when backward flow occurred during systolic periods. Methods Quantitative flow parameters, including forward flow volume (FFV), backward flow volume (BFV), and RF were estimated by two approaches: One derived from conventional ROI-averaged curve (bulk quantity) and the other in a pixel-wise manner to spatially reflect inhomogeneous flow profile (pixel-wise quantity). Eccentricity at systolic peak (Eccsys) was adopted as an index reflecting spatial flow inhomogeneity. Results Flow parameters derived from ROI-averaged curves on main pulmonary artery were significantly smaller than that of pixel-wise measurement (P<0.001). Difference between RFbulk and RFpx for the group of Eccsys > 0.3 appears greater compared to the group with Eccsys < 0.3. Thirteen out of 68 RF values (19%) were underrated while using bulk analysis. Conclusions The spatial-related flow parameters showed more consistency with the qualitative flow profile pattern for pulmonary arteries, and could be a decisive complement for diagnostic classification. ? 2017 Elsevier B.V. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/429968 | DOI: | 10.1016/j.ejrad.2017.05.027 | SDG/關鍵字: | artery blood flow; Article; child; clinical article; clinical decision making; disease classification; disease severity; Fallot tetralogy; female; human; male; nuclear magnetic resonance imaging; nuclear magnetic resonance scanner; phase contrast magnetic resonance imaging; preschool child; priority journal; pulmonary artery; pulmonary valve insufficiency; quantitative analysis; systolic blood pressure; clinical decision making; complication; diagnostic imaging; Fallot tetralogy; nuclear magnetic resonance imaging; postoperative complication; procedures; pulmonary valve insufficiency; reproducibility; Child, Preschool; Clinical Decision-Making; Female; Humans; Magnetic Resonance Imaging; Male; Postoperative Complications; Pulmonary Artery; Pulmonary Valve Insufficiency; Reproducibility of Results; Tetralogy of Fallot |
顯示於: | 生醫電子與資訊學研究所 |
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