|Title:||Phenethyl isothiocyanate enhances TRAIL-induced apoptosis in oral cancer cells and xenografts||Authors:||Yeh, Cheng-Chang
Kuo, Mark Yen-Ping
|Keywords:||Apoptosis; Death receptors; Oral cancer; PEITC; TRAIL||Issue Date:||Dec-2016||Publisher:||SPRINGER HEIDELBERG||Journal Volume:||20||Journal Issue:||9||Start page/Pages:||2343||Source:||Clinical oral investigations||Abstract:||
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been regarded as a promising candidate for cancer therapy. However, most of oral cancer cell lines are resistant to the TRAIL-induced cytotoxicity. The aim of this study was to investigate the ability of phenethyl isothiocyanate (PEITC) to sensitize TRAIL-induced apoptosis in TRAIL-resistant oral cancer cells and xenografts.
|Appears in Collections:||臨床牙醫學研究所|
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