https://scholars.lib.ntu.edu.tw/handle/123456789/434070
標題: | Preoperative proteinuria predicts adverse renal outcomes after coronary artery bypass grafting | 作者: | TAO-MIN HUANG VIN-CENT WU Young G.-H. YU-FENG LIN Shiao C.-C. Wu P.-C. WEN-YI LI HSI-YU YU Hu F.-C. JOU-WEI LIN YIH-SHARNG CHEN YEN-HUNG LIN SHOEI-SHEN WANG RON-BIN HSU FAN-CHI CHANG NAI-KUAN CHOU TZONG-SHINN CHU YU-CHANG YEH Tsai P.-R. JENQ-WEN HUANG SHUEI-LIONG LIN YUNG-MING CHEN Ko W.-J. KWAN-DUN WU |
公開日期: | 2011 | 卷: | 22 | 期: | 1 | 起(迄)頁: | 156-163 | 來源出版物: | Journal of the American Society of Nephrology | 摘要: | Whether preoperative proteinuria associates with adverse renal outcomes after cardiac surgery is unknown. Here, we performed a secondary analysis of a prospectively enrolled cohort of adult patients undergoing coronary artery bypass grafting (CABG) at a medical center and its two affiliate hospitals between 2003 and 2007. We excluded patients with stage 5 CKD or those who received dialysis previously. We defined proteinuria, measured with a dipstick, as mild (trace to 1+) or heavy (2+ to 4+). Among a total of 1052 patients, cardiac surgery-associated acute kidney injury (CSA-AKI) developed in 183 (17.4%) patients and required renal replacement therapy (RRT) in 50 (4.8%) patients. In a multiple logistic regression model, mild and heavy proteinuria each associated with an increased odds of CSA-AKI, independent of CKD stage and the presence of diabetes mellitus (mild: OR 1.66, 95% CI 1.09 to 2.52; heavy: OR 2.30, 95% CI 1.35 to 3.90). Heavy proteinuria also associated with increased odds of postoperative RRT (OR 7.29, 95% CI 3.00 to 17.73). In summary, these data suggest that preoperative proteinuria is a predictor of CSA-AKI among patients undergoing CABG. Copyright ? 2011 by the American Society of Nephrology. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-78651398215&doi=10.1681%2fASN.2010050553&partnerID=40&md5=b38aad81a9b860acfaba1b8ec94b5e2b https://scholars.lib.ntu.edu.tw/handle/123456789/434070 |
ISSN: | 1046-6673 | DOI: | 10.1681/ASN.2010050553 | SDG/關鍵字: | adrenalin; creatinine; dobutamine; dopamine; hemoglobin; isoprenaline; noradrenalin; acute kidney failure; adult; adverse outcome; anemia; article; cardiac surgery associated acute kidney injury; cardiopulmonary bypass; cerebrovascular accident; chronic kidney disease; chronic obstructive lung disease; comorbidity; congestive heart failure; coronary artery bypass graft; creatinine blood level; diabetes mellitus; dialysis; disease severity; female; heart infarction; heart left ventricle ejection fraction; heart surgery; hemodialysis patient; human; hypertension; major clinical study; male; meta analysis; peripheral occlusive artery disease; postoperative period; prediction; preoperative evaluation; priority journal; prospective study; proteinuria; renal replacement therapy; sensitivity analysis; Acute Kidney Injury; Aged; Cohort Studies; Coronary Artery Bypass; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Predictive Value of Tests; Preoperative Period; Prospective Studies; Proteinuria; Renal Replacement Therapy; Retrospective Studies; Risk Factors |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。