https://scholars.lib.ntu.edu.tw/handle/123456789/434189
標題: | Long-term evaluation of Carpentier-Edwards porcine bioprosthesis for rheumatic heart disease | 作者: | HSI-YU YU YI-LWUN HO Chu S.-H. YIH-SHARNG CHEN SHOEI-SHEN WANG Lin F.-Y. |
公開日期: | 2003 | 出版社: | Mosby Inc. | 卷: | 126 | 期: | 1 | 起(迄)頁: | 80-89 | 來源出版物: | Journal of Thoracic and Cardiovascular Surgery | 摘要: | Objectives: The clinical results of Carpentier-Edwards standard bioprosthesis have been extensively studied for valvular heart surgery in America and Europe. However, the data of long-term performance of Carpentier-Edwards standard porcine valve in areas with a high prevalence of rheumatic heart disease are still lacking. In this study, we assessed the clinical performance of Carpentier-Edwards standard porcine bioprostheses in a patient group with high prevalence of rheumatic heart disease. Methods: A total of 872 patients underwent valvular heart surgery with Carpentier-Edwards standard porcine bioprostheses replacement between 1975 and 1999 and the results were analyzed. Rheumatic etiology counts for 95% of the patients. Mean age of operation was 40 ± 14 years (mitral valve), 43 ± 19 years (aortic valve), and 45 ± 13 years (double valve). Follow-up was 95.6% complete and continued up to 24 years (total 7017 patient-years) with mean of 8.9 ± 5.1 years. Results: The operative mortality rate was 5.85%. Actuarial patient survival rates after discharge at 5, 10, 15, and 20 years were 92.5%, 83.8%, 72.3%, and 35.8%, respectively. A total of 442 cases received reoperation due to failure of bioprostheses. The mean duration to valve failure is 12.2 ± 0.4 years. Actuarial estimate of freedom from structural valvular failure at 5, 10, 15, and 20 years were 96.3%, 63.7%, 24.4%, and 7.7%, respectively. Conclusion: The long-term result of Carpentier-Edwards standard bioprostheses in the present patient group is satisfactory. However, freedom from valve failure is lower than that of Western series. Younger age at operation and higher prevalence of rheumatic etiology in this area are possible causes. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0042343782&doi=10.1016%2fS0022-5223%2802%2973608-8&partnerID=40&md5=9cd456ed04cbec9f942f2c485fb49d56 https://scholars.lib.ntu.edu.tw/handle/123456789/434189 |
ISSN: | 0022-5223 | DOI: | 10.1016/S0022-5223(02)73608-8 | SDG/關鍵字: | warfarin; adolescent; adult; aged; animal tissue; aorta valve; article; bioprosthesis; female; follow up; heart valve surgery; human; long term care; major clinical study; male; mitral valve; nonhuman; prevalence; priority journal; prosthesis failure; rheumatic heart disease; school child; surgical mortality; surgical technique; survival; survival time; swine; treatment outcome |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。