https://scholars.lib.ntu.edu.tw/handle/123456789/434358
標題: | Advantages of laparoscopic splenectomy for splenomegaly due to hematologic diseases | 作者: | RAY-HWANG YUAN Chen S.-B. Lee W.-J. Yu S.-C. |
關鍵字: | β- thalassemia; Idiopathic thrombocytopenic purpura; Laparoscopic splenectomy | 公開日期: | 1998 | 卷: | 97 | 期: | 7 | 起(迄)頁: | 485-489 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Recent advancements in laparoscopic surgery have made laparoscopic splenectomy possible. We retrospectively compared the outcomes of laparoscopic versus open splenectomy in patients with idiopathic thrombocytopenic purpura (ITP) or β-thalassemia. From July 1993 to July 1997, 52 patients (ITP, 43 cases; β-thalassemia, 9 cases) underwent either laparoscopic (30 patients, 9 men, 21 women; average age, 36.9 years) or conventional open splenectomy (22 patients, 5 men, 17 women; average age, 34.3 years). The two groups were similar in terms of sex, age, diagnosis, duration of disease, preoperative platelet count, and spleen size. The mean surgical time, estimated amount of blood loss, duration of postoperative recovery, analgesic usage, and complications were compared between the two groups. Laparoscopic splenectomy was successful in 29 (97%) of the 30 patients. The mean surgical time in the laparoscopy group was longer than in the open splenectomy group (190.6 vs 113.9 minutes, p < 0.01). The laparoscopy group had earlier postoperative oral intake (15.2 vs 52.6 hours, p < 0.01), less usage of analgesics (meperidine 50 mg/unit, 1.1 vs 2.8 units, p < 0.01) and a shorter postoperative hospital stay (4.1 vs 6.8 days, p < 0.01). The estimated blood loss, incidence of accessory spleen, surgical complication rate, and recurrence rate of thrombocytopenia were similar in the two groups. Our findings show that laparoscopic splenectomy in patients with ITP or β-thalassemia is as safe as the open approach. While laparoscopy required a longer surgical time, the recovery period was shorter, analgesic use was less, and physical discomfort was less severe. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031847932&partnerID=40&md5=af576f8ca20aa09e69512b79975adead https://scholars.lib.ntu.edu.tw/handle/123456789/434358 |
ISSN: | 0929-6646 | SDG/關鍵字: | adolescent; adult; aged; article; bleeding; child; controlled study; female; hematologic disease; human; laparoscopic surgery; length of stay; major clinical study; male; operation duration; postoperative complication; risk assessment; school child; splenectomy; splenomegaly; surgical risk; treatment outcome; Adolescent; Adult; Aged; beta-Thalassemia; Child; Female; Humans; Laparoscopy; Male; Middle Aged; Purpura, Thrombocytopenic, Idiopathic; Retrospective Studies; Splenectomy; Splenomegaly; Statistics, Nonparametric; Treatment Outcome |
顯示於: | 醫學系 |
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