https://scholars.lib.ntu.edu.tw/handle/123456789/434997
Title: | 1,2-Ethanedithiol-induced erythema multiforme-like contact dermatitis | Authors: | Tjiu J.-W. CHIA-YU CHU Sun C.-C. |
Issue Date: | 2004 | Journal Volume: | 84 | Journal Issue: | 5 | Start page/Pages: | 393-396 | Source: | Acta Dermato-Venereologica | Abstract: | Contact dermatitis simulating erythema multiforme can be caused by many allergens. The chemical agent 1,2-ethanedithiol, which serves as a protective group in chemical synthesis, has hitherto only been implicated as an irritant. We report on a 22-year-old female chemistry student who developed widespread erythema multiforme-like lesions after local contact with 1,2-ethanedithiol. Many target lesions were observed bilaterally on her hands, forearms, arms, and on her forehead. One such lesion was histologically compatible with erythema multiforme. The patient had a positive patch test to 1,2-ethanedithiol, whereas none of 30 healthy subjects showed a positive reaction. However, eight of the 30 controls (26.7%) developed irritant reactions to 1,2-ethanedithiol. Cautious handling of the compound is a prudent precaution. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-4744349321&doi=10.1080%2f00015550410033571&partnerID=40&md5=8301ffa920bc85b6226561cc569909dc https://scholars.lib.ntu.edu.tw/handle/123456789/434997 |
ISSN: | 0001-5555 | DOI: | 10.1080/00015550410033571 | SDG/Keyword: | 1,2 ethanedithiol; dithiol derivative; methylprednisolone; prednisolone; unclassified drug; adult; article; case report; contact dermatitis; controlled study; differential diagnosis; erythema multiforme; female; histopathology; human; patch test; priority journal; skin biopsy; skin manifestation; steroid therapy; Adrenal Cortex Hormones; Adult; Dermatitis, Contact; Diagnosis, Differential; Erythema Multiforme; Ethylene Glycol; Female; Humans; Irritants; Male; Methylprednisolone; Middle Aged; Patch Tests; Prednisolone |
Appears in Collections: | 醫學系 |
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