https://scholars.lib.ntu.edu.tw/handle/123456789/435122
標題: | Hydroa vacciniforme-like primary cutaneous CD8-positive T-cell lymphoma | 作者: | Chen H.-H. Hsiao C.-H. HSIEN-CHING CHIU |
公開日期: | 2002 | 卷: | 147 | 期: | 3 | 起(迄)頁: | 587-591 | 來源出版物: | British Journal of Dermatology | 摘要: | An 8-year-old Taiwanese girl had a 6-month history of a relapsing papulovesicular eruption on her face that resembled hydroa vacciniforme (HV). Histologically, there was a dense infiltration of large atypical lymphocytic cells expressing CD8. TCR-γ gene rearrangement study revealed a monoclonal band present in the DNA extracted from the specimen. A diagnosis of CD8+ cutaneous T-cell lymphoma (CTCL) was made. The patient was treated with Chinese herbal drugs and her skin lesions waxed and waned. At this writing, 11 months after establishment of the diagnosis, the skin lesions have been limited to the facial area and no definite evidence of systemic involvement is noted. To our knowledge, this is the first case of CD8+ primary CTCL with clinical features resembling HV. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036050783&doi=10.1046%2fj.1365-2133.2002.04862.x&partnerID=40&md5=b0bea048cc1c3261a6939f738ac752c4 https://scholars.lib.ntu.edu.tw/handle/123456789/435122 |
ISSN: | 0007-0963 | DOI: | 10.1046/j.1365-2133.2002.04862.x | SDG/關鍵字: | CD8 antigen; herbaceous agent; antigen expression; article; cancer diagnosis; case report; cell size; cell structure; Chinese herb; clinical feature; differential diagnosis; disease severity; DNA determination; DNA extraction; face; female; gene rearrangement; herbal medicine; histopathology; human; human tissue; hydroa vacciniforme; immunohistochemistry; lymphocytic infiltration; papular skin disease; physical examination; priority journal; rash; relapse; school child; systemic disease; T cell lymphoma; T lymphocyte receptor gene; treatment outcome; CD8-Positive T-Lymphocytes; Child; Facial Dermatoses; Female; Humans; Hydroa Vacciniforme; Lymphoma, T-Cell, Cutaneous; Skin Neoplasms |
顯示於: | 醫學系 |
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