https://scholars.lib.ntu.edu.tw/handle/123456789/448836
標題: | BMI-based approach reveals direct impact of metal dust exposure on influenza-associated lung function decrement risk in smelters | 作者: | Cheng Y.-H. CHUNG-MIN LIAO |
關鍵字: | Body mass index (BMI); Influenza; Lung function; Metal dust; Risk assessment; Smelters | 公開日期: | 2012 | 卷: | 235-236 | 起(迄)頁: | 210-217 | 來源出版物: | Journal of Hazardous Materials | 摘要: | Metal dust exposure strongly affects human health, especially for smelters. Little is known, however, about the impact of metal dust exposure on influenza-associated lung function decrement risk in smelters. Different body mass index (BMI) groups were also associated with respiratory diseases. The purpose of this study was to use a probabilistic risk assessment approach to explicitly link occupational metal dust exposure, BMI-correlated health effects, and influenza-associated lung function decrements to investigate potential risk among smelters. Here we showed that (i) influenza A-associated metal dust exposure in SiMn/FeMn/FeCr smelters had slightly higher health risks than that in FeSi/Si-metal's, (ii) BMI?35 had the highest risk in respiratory infection exacerbations, and (iii) the estimated smelting metal dust induced forced expiratory volume in 1s (FEV1) decreasing rates were 0.59 and 1.11m3mg-1 for FeSi/Si-metal and SiMn/FeMn/FeCr smelters, respectively. Our results suggested that smelters better be aware of severe weight gains (e.g., BMIs from 27-40) because it is likely to lead to 17-25% decrements in lung function. This study provides a novel probabilistic risk assessment framework to quantitatively assess the occupational health risk posed by metal dust exposure associated with influenza infection based on BMI measures. ? 2012 Elsevier B.V. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/448836 | ISSN: | 0304-3894 | DOI: | 10.1016/j.jhazmat.2012.07.043 | SDG/關鍵字: | Body mass index; Influenza; Lung function; Metal dust; Smelters; Biological organs; Dust control; Health; Health risks; Industrial hygiene; Metals; Pulmonary diseases; Risk assessment; Risk perception; Smelting; chromium phosphate; iron derivative; manganese derivative; silicon derivative; body mass; dust; health impact; health risk; influenza; metal; pollution exposure; probability; public health; respiratory disease; risk assessment; smelting; adult; article; body mass; clinical article; disease exacerbation; dust; female; forced expiratory volume; human; infection risk; influenza A; lung function; male; occupational exposure; outcome assessment; probability; quantitative analysis; risk assessment; smelter; weight gain; Adult; Air Pollutants, Occupational; Body Mass Index; Dust; Female; Forced Expiratory Volume; Humans; Influenza, Human; Lung; Male; Metallurgy; Metals, Heavy; Occupational Exposure; Risk Assessment; Silicon; Young Adult |
顯示於: | 生物環境系統工程學系 |
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