https://scholars.lib.ntu.edu.tw/handle/123456789/456360
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Lazarides A.L. | en_US |
dc.contributor.author | Eward W.C. | en_US |
dc.contributor.author | Speicher P.J. | en_US |
dc.contributor.author | CHUN-HAN HOU | en_US |
dc.contributor.author | Nussbaum D.P. | en_US |
dc.contributor.author | Green C. | en_US |
dc.contributor.author | Blazer D.G. | en_US |
dc.contributor.author | III | en_US |
dc.contributor.author | Kirsch D.G. | en_US |
dc.contributor.author | Brigman B.E. | en_US |
dc.creator | Lazarides A.L.;Eward W.C.;Speicher P.J.;Chun-Han Hou;Nussbaum D.P.;Green C.;Blazer D.G.;Iii;Kirsch D.G.;Brigman B.E. | - |
dc.date.accessioned | 2020-02-10T06:01:57Z | - |
dc.date.available | 2020-02-10T06:01:57Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1357-714X | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84929630315&doi=10.1155%2f2015%2f186581&partnerID=40&md5=0c37b877d6eba7e077b9cc110bbdd296 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/456360 | - |
dc.description.abstract | Objective. This study investigated patterns of utilization of radiation therapy (RT) and correlated this with overall survival by assessing patients with well-differentiated soft tissue sarcoma of the extremity (STS-E) in the National Cancer Database (NCDB). Methods. All patients diagnosed with well-differentiated STS-E between 1998 and 2006 were identified in the NCDB. Patients were stratified by use of surgery alone versus use of adjuvant RT after surgery and analyzed using multivariate analysis, Kaplan-Meier analysis, and propensity matching. Results. 2113 patients with well-differentiated STS-E were identified in the NCDB for inclusion with a mean follow-up time of 74 months. 69% of patients were treated with surgery alone, while 26% were treated with surgery followed by adjuvant RT. Patients undergoing amputation were less likely to receive adjuvant RT. There was no difference in overall survival between patients with well-differentiated STS treated with surgery alone and those patients who received adjuvant RT. Conclusions. In the United States, adjuvant RT is being utilized in a quarter of patients being treated for well-differentiated STS-E. While the use of adjuvant RT may be viewed as a means to facilitate limb salvage, this large national database review confirms no survival benefit, regardless of tumor size or margin status. Copyright ? 2015 Alexander L. Lazarides et al. | - |
dc.publisher | Hindawi Publishing Corporation | - |
dc.relation.ispartof | Sarcoma | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; aged; cancer adjuvant therapy; cancer radiotherapy; cancer surgery; cancer survival; controlled study; female; follow up; human; limb amputation; limb salvage; limb tumor; long term survival; major clinical study; male; overall survival; priority journal; retrospective study; Review; soft tissue sarcoma; treatment outcome; well differentiated liposarcoma; well differentiated soft tissue sarcoma of the extremity | - |
dc.title | The Use of Radiation Therapy in Well-Differentiated Soft Tissue Sarcoma of the Extremities: An NCDB Review | en_US |
dc.type | Review | en |
dc.identifier.doi | 10.1155/2015/186581 | - |
dc.identifier.scopus | 2-s2.0-84929630315 | - |
dc.relation.journalvolume | 2015 | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Review | - |
item.grantfulltext | none | - |
crisitem.author.dept | Orthopedic Surgery | - |
crisitem.author.dept | Orthopedic Surgery-NTUH | - |
crisitem.author.orcid | 0000-0002-3850-0997 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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