https://scholars.lib.ntu.edu.tw/handle/123456789/457918
標題: | Liver transplantation for acute hepatic failure | 作者: | YAO-MING WU MING-CHIH HO REY-HENG HU Ko W.-J. PEI-MING YANG Lai M.-Y. PO-HUANG LEE |
公開日期: | 2004 | 卷: | 36 | 期: | 8 | 起(迄)頁: | 2226-2227 | 來源出版物: | Transplantation Proceedings | 摘要: | The mortality rate of acute hepatic failure (AHF) with conservative treatment is 40% to 90%, depending on the etiology. Hepatitis B infection is the major cause of AHF in Asia. In this study, we examined the role of liver transplantation for adult patients with AHF. Sixteen patients with AHF received liver transplants in the past 6 years. Eight patients received cadaveric donor and another 8 living-related donor grafts. Fifteen patients suffered from hepatitis B-related disease and 1 had drug-induced AHF. Extracorporeal charcoal hemoperfusion was used as a bridge to liver transplantation in the first 2 patients and plasma exchange was used in the following patients. One patient died 1 month after the operation due to primary nonfunction. The other 15 patients are alive with good graft function at 2 months to 6 years follow-up. The success rate is 94%. Postoperative complications included infection in 10 patients (62.5%), acute rejection in 4 patients (25%), and biliary complication in 2 patients (12.5%). No neurological complications were noted. Liver transplantation is the most effective treatment for patients with AHF. Living donors may be considered due to the organ shortage and the critical patient disease. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-9244259091&doi=10.1016%2fj.transproceed.2004.08.062&partnerID=40&md5=befeb9ace5693a735d3c4a32f9d5ddc6 https://scholars.lib.ntu.edu.tw/handle/123456789/457918 |
ISSN: | 0041-1345 | DOI: | 10.1016/j.transproceed.2004.08.062 | SDG/關鍵字: | acute graft rejection; adolescent; adult; bile leakage; cadaver donor; cause of death; clinical article; conference paper; extracorporeal circulation; female; follow up; graft survival; hemoperfusion; hepatitis B; human; liver failure; liver transplantation; living donor; male; neurological complication; organ donor; plasmapheresis; postoperative complication; postoperative infection; priority journal; Cadaver; Family; Gallbladder Diseases; Humans; Infection; Liver Failure, Acute; Liver Transplantation; Living Donors; Postoperative Complications; Retrospective Studies; Tissue Donors; Treatment Outcome |
顯示於: | 醫學系 |
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