https://scholars.lib.ntu.edu.tw/handle/123456789/458265
標題: | Integrated backscatter for quantification and risk stratification of blood stagnation in left atrial appendages of patients with rheumatic mitral stenosis | 作者: | YI-LWUN HO CHAU-CHUNG WU Lin, Lung-Chun MING-FONG CHEN Lee, Y.-T. Huang, P.-J. |
關鍵字: | Atrial fibrillation | Integrated backscatter | Left atrial appendage thrombosis | Mitral stenosis;Atrial fibrillation; Integrated backscatter; Left atrial appendage thrombosis; Mitral stenosis | 公開日期: | 2000 | 卷: | 93 | 期: | 1-2 | 來源出版物: | Cardiology | 摘要: | This study was designed to quantify the blood stagnation in left atrial appendages (LAA) of patients with rheumatic mitral stenosis, and to stratify the risk of spontaneous echo contrast (SEC) for thrombus formation. A total of 45 patients were enrolled in this study. Thirty of the 45 patients had rheumatic mitral stenosis. All the above patients were evaluated for LAA contractility by transesophageal echocardiography. Acoustic density of the stagnant blood was assessed using the integrated backscatter (IBS) mode. Multivariate linear regression analysis showed that the significant independent variables determining relative IBS in LAA were the mitral valve area (p = 0.02) and the atrial fibrillation rhythm (p = 0.0003). In patients with mitral stenosis, the IBS in LAA correlated well with the presence of thrombus (p = 0.004) and SEC (p = 0.002). Using the relative IBS in LAA with 6.8 dB as the cutoff value, the diagnostic sensitivity, specificity, positive predictive value, negative predictive value and accuracy of SEC formation in LAA was 83, 86,95, 60 and 83%, respectively. Using the relative IBS in LAA with 10.0 dB as the cutoff value, the diagnostic sensitivity, specificity, positive predictive value, negative predictive value and accuracy of SEC with thrombus formation in LAA was 80, 80, 67, 89 and 80%, respectively. In conclusion, the blood stasis in LAA can be objectively quantified using IBS. Utilizing different cutoff values, the acoustic densitometry in LAA enables identification of stagnant blood which represents a risk for the development of either SEC only or SEC with thrombus formation. Copyright (C) 2000 S. Karger AG, Basel. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/458265 | ISSN: | 00086312 | DOI: | 14056806 10.1159/000007011 |
SDG/關鍵字: | adult; aged; article; clinical article; controlled study; female; heart atrium contraction; heart atrium fibrillation; heart left atrium; heart rhythm; hemostasis; human; male; mitral valve stenosis; priority journal; rheumatic heart disease; risk assessment; thrombogenesis; transesophageal echocardiography |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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