https://scholars.lib.ntu.edu.tw/handle/123456789/458482
標題: | Successful pregnancy in a gonadectomized woman with 46,XY gonadal dysgenesis and gonadoblastoma | 作者: | MEI-JOU CHEN JEHN-HSIAHN YANG Mao T.-L HONG-NERNG HO YU-SHIH YANG |
公開日期: | 2005 | 卷: | 84 | 期: | 1 | 起(迄)頁: | 217 | 來源出版物: | Fertility and Sterility | 摘要: | Objective: To present a case of successful pregnancy after conservative bilateral gonadectomy without adjuvant chemotherapy and radiotherapy in a 46,XY gonadal dysgenetic woman with gonadoblastoma and malignant germ cell tumor. Design: Case report. Setting: Infertility center in university hospital. Patient(s): An 18-year-old female with 46,XY karyotype underwent bilateral gonadectomy, and the pathology revealed gonadoblastoma with malignant mixed germ cell tumor. Intervention(s): Chromosomal analysis, bilateral gonadectomy, donor oocyte, and IVF program. Main Outcome Measure(s): Tumor markers and pregnancy result. Result(s): The patient was free from tumor recurrence after 13 years' follow-up. A successful twin pregnancy was achieved after oocyte donation and IVF. Conclusion(s): Gonadectomy without adjuvant therapies could be done in 46,XY gonadal dysgenetic women with gonadoblastoma in view of preservation of future fertility. ?2005 by American Society for Reproductive Medicine. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/458482 | ISSN: | 0015-0282 | DOI: | 10.1016/j.fertnstert.2004.11.087 | SDG/關鍵字: | adult; anamnesis; article; case report; chromosome analysis; clinical examination; echography; female; follow up; germ cell tumor; gonadal dysgenesis; gonadectomy; gonadoblastoma; human; oocyte donation; pregnancy; priority journal; tumor recurrence; twin pregnancy; university hospital |
顯示於: | 醫學系 |
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