https://scholars.lib.ntu.edu.tw/handle/123456789/458617
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | YU-LI CHEN | en_US |
dc.contributor.author | Ho C.-M. | en_US |
dc.contributor.author | CHI-AN CHEN | en_US |
dc.contributor.author | YING-CHENG CHIANG | en_US |
dc.contributor.author | Huang C.-Y. | en_US |
dc.contributor.author | CHANG-YAO HSIEH | en_US |
dc.contributor.author | WEN-FANG CHENG | en_US |
dc.creator | Chen Y.-L.;Ho C.-M.;Chen C.-A.;Chiang Y.-C.;Huang C.-Y.;Hsieh C.-Y.;Wen-Fang Cheng | - |
dc.date.accessioned | 2020-02-14T02:49:58Z | - |
dc.date.available | 2020-02-14T02:49:58Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0020-7292 | - |
dc.identifier.uri | 2-s2.0-78650751467 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/458617 | - |
dc.description.abstract | Objective: To evaluate the outcomes of patients with stage IB1-IIA cervical adenocarcinoma treated by various modalities in order to formulate a better treatment strategy. Methods: The impact of various treatment modalities on the prognosis of 258 patients with stage IB1-IIA cervical adenocarcinoma was investigated. The therapeutic modalities included radical surgery (n = 174); radical surgery followed by adjuvant radiation therapy (RT), such as RT alone or concurrent chemo-radiotherapy (CCRT) (n = 46); or primary RT or CCRT (n = 38). Results: As compared with patients in the surgery-only group, patients with 1 postoperative major risk who underwent surgery followed by RT or CCRT had a significantly higher likelihood of disease relapse (2.3-fold, P = 0.041) and disease-related death (2.9-fold, P = 0.014). The likelihood of recurrence (P = 0.32) and death (P = 0.58) did not differ between patients who underwent adjuvant RT or CCRT for 1 major risk factor and those who underwent primary RT or CCRT. By contrast, patients with more than 1 major risk factor had a higher likelihood of disease recurrence (2.9-fold, P = 0.037) and disease-related death (3.4-fold, P = 0.051) than those who underwent primary RT or CCRT. Conclusion: Radical surgery is recommended for patients with stage IB1-IIA cervical adenocarcinomas without contraindications. Those with more than 1 postoperative pathologic risk factor had the worst prognosis despite adjuvant RT or CCRT. ? 2010 International Federation of Gynecology and Obstetrics. | - |
dc.relation.ispartof | International Journal of Gynecology and Obstetrics | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | antineoplastic agent; adenocarcinoma; adjuvant therapy; adult; article; cancer recurrence; cancer relapse; cancer staging; controlled study; female; human; major clinical study; mortality; priority journal; recurrent disease; risk factor; uterine cervix carcinoma | - |
dc.title | Impact of various treatment modalities on the outcome of stage IB1-IIA cervical adenocarcinoma | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.ijgo.2010.08.016 | - |
dc.identifier.scopus | 56601533000 | - |
dc.relation.pages | 135-139 | - |
dc.relation.journalvolume | 112 | - |
dc.relation.journalissue | 2 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Obstetrics & Gynecology | - |
crisitem.author.dept | Obstetrics & Gynecology-NTUH | - |
crisitem.author.dept | Obstetrics&Gynecology-NTUHYL | - |
crisitem.author.dept | Obstetrics & Gynecology-NTUH | - |
crisitem.author.dept | Obstetrics & Gynecology | - |
crisitem.author.dept | Obstetrics & Gynecology | - |
crisitem.author.dept | Obstetrics & Gynecology-NTUH | - |
crisitem.author.dept | Surgery-NTUCC | - |
crisitem.author.dept | Obstetrics & Gynecology-NTUH | - |
crisitem.author.dept | Oncology-NTUH | - |
crisitem.author.dept | Obstetrics & Gynecology | - |
crisitem.author.dept | Obstetrics & Gynecology | - |
crisitem.author.dept | Obstetrics & Gynecology-NTUH | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Oncology | - |
crisitem.author.dept | Surgery-NTUCC | - |
crisitem.author.orcid | 0000-0002-9742-4752 | - |
crisitem.author.orcid | 0000-0001-6670-7939 | - |
crisitem.author.orcid | 0000-0002-8958-5222 | - |
crisitem.author.orcid | 0000-0002-3282-6304 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital Yun-Lin Branch | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
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