https://scholars.lib.ntu.edu.tw/handle/123456789/460353
Title: | A protocol of electroejaculation and systematic assisted reproductive technology achieved high efficiency and efficacy for pregnancy for anejaculatory men with spinal cord injury | Authors: | JENG-YI SHIEH SHEE-UAN CHEN Wang Y.-H HONG-CHIANG CHANG HONG-NERNG HO YU-SHIH YANG |
Issue Date: | 2003 | Journal Volume: | 84 | Journal Issue: | 4 | Start page/Pages: | 535-540 | Source: | Archives of Physical Medicine and Rehabilitation | Abstract: | Objective: To help anejaculatory men with spinal cord injury (SCI) to procreate. Design: Prospective, clinical study. Setting: A team of physiatrists, urologists, and gynecologists at a university hospital in Taiwan. Participants: Ten infertile men with SCI seen at our hospital between 1995 and 2001. Interventions: Electroejaculation induced their seminal emission. Depending on semen parameters, the couples were treated with intrauterine insemination (IUI), intracytoplasmic sperm injection (ICSI), surgical retrieval of sperm, cryopreservation of sperm, or donor sperm. Main Outcome Measures: Fertilization and pregnancy. Results: Ten couples underwent assisted reproductive technology (ART). One couple achieved pregnancy after the second cycle of electroejaculation and IUI. Seven couples underwent 8 cycles of ICSI, 4 cycles with fresh electroejaculates, 2 with cryopreserved samples, and 2 with cryopreserved samples with addition of pentoxifylline. Seven (88%) clinical pregnancies were achieved, 2 of which ended with spontaneous abortion. One couple accomplished pregnancy by ICSI with cryopreserved sperm from vasal aspiration. The percentages of fertilization and pregnancy of ICSI cycles using sperm from men with SCI were comparable to men without SCI. One couple attained pregnancy by using donor sperm. The cumulative successful pregnancy rate per couple was 80% (8/10). Conclusion: Electroejaculation and systematic ART are highly efficient for achieving pregnancy with the spouses of men with SCI. The neurologic deficit and electroejaculation did not affect the outcome of ICSI. Using cryopreserved sperm for ICSI may reduce risk from electroejaculation or surgery. ? 2003 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/460353 | ISSN: | 0003-9993 | DOI: | 10.1053/apmr.2003.50126 | SDG/Keyword: | pentoxifylline; adult; article; clinical article; clinical protocol; cryopreservation; ejaculation; fertilization; human; intracytoplasmic sperm injection; intrauterine insemination; male; pregnancy rate; prospective study; reproductive procedures; sperm preservation; spinal cord injury; Taiwan |
Appears in Collections: | 醫學系 |
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