https://scholars.lib.ntu.edu.tw/handle/123456789/461740
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | YU-TING CHANG | en_US |
dc.contributor.author | YU-WEN TIEN | en_US |
dc.contributor.author | YUNG-MING JENG | en_US |
dc.contributor.author | CHING-YAO YANG | en_US |
dc.contributor.author | PO-CHIN LIANG | en_US |
dc.contributor.author | Wong J.-M. | en_US |
dc.contributor.author | MING-CHU CHANG | en_US |
dc.creator | Chang Y.-T.;Tien Y.-W.;Jeng Y.-M.;Ching-Yao Yang;Liang P.-C.;Wong J.-M.;Chang M.-C. | - |
dc.date.accessioned | 2020-02-20T02:56:59Z | - |
dc.date.available | 2020-02-20T02:56:59Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937965210&doi=10.1097%2fMD.0000000000000797&partnerID=40&md5=0574ad7f1c926031cc4cfd3412e236dd | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/461740 | - |
dc.description.abstract | Distinguishing between benign and malignant pancreatic cysts remains a clinical challenge. The aim of this study was to investigate the influence of body mass index (BMI) and preoperative clinical and cyst features, as described by the International Consensus Guidelines, on malignancy in patients with pancreatic mucinous cystic neoplasms (PMCNs). A retrospective cohort study was performed on patients with PMCNs who underwent surgical resection between January 1994 and June 2014. Preoperative BMI, clinical demographic data, cystic features, tumor markers, and surgical pathology results were analyzed. Predictors of malignancy were determined by univariate and multivariate analysis using logistic regression. One hundred sixty-four cases of PMCNs, including 106 intraductal papillary mucinous neoplasms (IPMNs) and 58 mucinous cystic neoplasms (MCNs), were analyzed. On univariate analysis, older age (P=0.008), male sex (P=0.007), high-risk stigmata (P=0.007), diabetes mellitus (DM; P=0.008), and BMI >25 (P<0.001) were associated with malignancy. Multivariate analysis found that BMI >25 (odds ratio, 3.99; 95% confidence interval: 1.60-10) was an independent predictor of malignancy. In subgroup analysis, BMI >25 was an independent predictor of malignancy in IPMNs but not in MCNs. Overweight patientswith IPMNs have a higher risk of malignancy and should be followed closely or undergo resection. The operative strategy for PMCNs should consider cyst-related and patient-related risk factors. ? 2015 Wolters Kluwer Health, Inc. | - |
dc.publisher | Lippincott Williams and Wilkins | - |
dc.relation.ispartof | Medicine (United States) | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; Article; body mass; cancer surgery; cohort analysis; diabetes mellitus; disease association; female; high risk patient; histopathology; human; intraductal papillary mucinous tumor; major clinical study; male; middle aged; mucinous cystic neoplasm; obesity; pancreas tumor; pancreatic mucinous cystic neoplasm; predictor variable; preoperative evaluation; priority journal; retrospective study; risk factor; Taiwan; age; complication; multivariate analysis; Neoplasms, Cystic, Mucinous, and Serous; obesity; Pancreatic Neoplasms; pathology; sex difference; Age Factors; Female; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasms, Cystic, Mucinous, and Serous; Overweight; Pancreatic Neoplasms; Retrospective Studies; Risk Factors; Sex Factors | - |
dc.title | Overweight Increases the Risk of Malignancy in Patients with Pancreatic Mucinous Cystic Neoplasms | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1097/MD.0000000000000797 | - |
dc.identifier.pmid | 25997051 | - |
dc.identifier.scopus | 2-s2.0-84937965210 | - |
dc.relation.journalvolume | 94 | - |
dc.relation.journalissue | 20 | - |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Pathology | - |
crisitem.author.dept | Pathology-NTUH | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Medical Imaging-NTUH | - |
crisitem.author.dept | Medical Imaging-NTUHHC | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Integrated Diagnostics and Therapeutics-NTUH | - |
crisitem.author.orcid | 0000-0002-5912-3406 | - |
crisitem.author.orcid | 0000-0002-9126-2705 | - |
crisitem.author.orcid | 0000-0002-3878-4491 | - |
crisitem.author.orcid | 0000-0001-6312-3719 | - |
crisitem.author.orcid | 0000-0002-6674-2926 | - |
crisitem.author.orcid | 0000-0003-4896-7838 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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