https://scholars.lib.ntu.edu.tw/handle/123456789/465835
標題: | The effect of mesalazine (5-ASA) enemas in patients with mild to moderate proctitis or proctosigmoiditis - A preliminary report in Taiwan | 作者: | MING-JIUM SHIEH Wong J.-M. Wang C.-Y. |
關鍵字: | Distal ulcerative colitis; Mesalazine (5-ASA) enema | 公開日期: | 1999 | 卷: | 11 | 期: | 5 | 起(迄)頁: | 285-288 | 來源出版物: | Biomedical Engineering - Applications, Basis and Communications | 摘要: | We conducted a clinical trial at a referral center (National Taiwan University Hospital) to evaluate the efficacy and safety of mesalazine (5-ASA) enemas in fourteen Taiwanese patients with relapse of distal ulcerative colitis (UC). Clinical, endoscopic and histological assessments were done at entry and every four weeks. Our results showed that short-term therapy with nightly 5-ASA enemas induced prompt remission in a majority of patients previously unresponsive to conventional therapy. Side effects were few and insignificant. No significant changes were observed in hematology, blood chemistry, or urinalysis. None was withdrawn from the study following initial selection for this trial. Our preliminary results indicated that 5-ASA enemas are an effective, well-tolerated medication for the treatment of UC confined to the distal colon. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033604152&partnerID=40&md5=1d9c87550534a9d8708e83874a52a5e7 https://scholars.lib.ntu.edu.tw/handle/123456789/465835 |
ISSN: | 1016-2372 | SDG/關鍵字: | enema; mesalazine; adult; article; clinical article; clinical trial; drug efficacy; drug induced disease; drug safety; drug tolerability; female; human; male; proctitis; relapse; remission; Taiwan; ulcerative colitis; Blood; Diseases; Endoscopy; Enemas; Patient treatment |
顯示於: | 醫學工程學研究所 |
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