https://scholars.lib.ntu.edu.tw/handle/123456789/466008
標題: | Laparoscopic splenectomy for idiopathic thrombocytopenic purpura | 作者: | Wu J.-M. I-RUE LAI RAY-HWANG YUAN Yu S.-C. |
公開日期: | 2004 | 卷: | 187 | 期: | 6 | 起(迄)頁: | 720-723 | 來源出版物: | American Journal of Surgery | 摘要: | Background Laparoscopic splenectomy (LS) has become the treatment of choice for patients with idiopathic thrombocytopenic purpura (ITP) who do not respond to medical treatment. Long-term follow-up data of LS for ITP are scarce. Methods From May 1997 to December 2002, we performed 67 LS for patients with ITP. Data were assessed retrospectively. Results LS was successfully attempted in all 67 patients. There was no surgical mortality. Three postoperative complications (5%) were encountered. The mean operative time decreased significantly from 176.2 minutes in the first 41 cases to 125.2 minutes in the last 26 cases. The mean postoperative hospital stay was 3.2 days. Accessory spleens were found in 3 patients (5%) during the LS. The mean follow-up interval was 23.3 months. The initial response to LS was 83%, and overall remission of ITP was 74%. The preoperative effect of steroid therapy had no significant influence on postoperative remission rate. More significant indicators of LS effectiveness were either an immediate postoperative platelet count surge or an immediate postoperative platelet count ?100,000/μL. Conclusions LS can be performed safely with a satisfactory remission rate for patients with ITP who do not respond to medical treatment. Our results indicated that an immediate postoperative platelet count surge and/or an immediate postoperative platelet count ?100,000/μL were positive predictors of long-term remission after LS for ITP. ? 2004 Excerpta Medica Inc. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-2942573508&doi=10.1016%2fj.amjsurg.2003.11.032&partnerID=40&md5=7927b4458819cd6d613a756a2d2f34cd https://scholars.lib.ntu.edu.tw/handle/123456789/466008 |
ISSN: | 0002-9610 | DOI: | 10.1016/j.amjsurg.2003.11.032 | SDG/關鍵字: | antiandrogen; cyclophosphamide; immunoglobulin; steroid; accessory spleen; adolescent; adult; aged; article; drug hypersensitivity; female; hospitalization; human; idiopathic thrombocytopenic purpura; laparoscopic surgery; major clinical study; male; operation duration; plate count; postoperative complication; premedication; preoperative care; priority journal; remission; school child; splenectomy; steroid therapy; surgical mortality; treatment outcome; Adult; Female; Humans; Laparoscopy; Length of Stay; Male; Platelet Count; Postoperative Complications; Postoperative Period; Purpura, Thrombocytopenic, Idiopathic; Remission Induction; Retrospective Studies; Splenectomy; Time Factors |
顯示於: | 解剖學暨細胞生物學科所 |
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