https://scholars.lib.ntu.edu.tw/handle/123456789/470862
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Ho C.-K. | en_US |
dc.contributor.author | Lo W.C.H. | en_US |
dc.contributor.author | PEI-HSIN HUANG | en_US |
dc.contributor.author | Wu M.-T. | en_US |
dc.contributor.author | Christiani D.C. | en_US |
dc.contributor.author | CHIN-TARNG LIN | en_US |
dc.creator | Ho C.-K.;Lo W.C.H.;Pei-Hsin Huang;Wu M.-T.;Christiani D.C.;Lin C.-T. | - |
dc.date.accessioned | 2020-03-05T08:16:47Z | - |
dc.date.available | 2020-03-05T08:16:47Z | - |
dc.date.issued | 1999 | - |
dc.identifier.issn | 1351-0711 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032957884&doi=10.1136%2foem.56.6.426&partnerID=40&md5=200a9d7c8102e5a2b92875135544f705 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/470862 | - |
dc.description.abstract | Sulphuric acid vapour has been suspected of being an industrial carcinogen. In this study, a cluster is presented of three patients with nasopharyngeal carcinoma (NPC) who worked in the same building of a telecommunications conveyance station in southern Taiwan with long term exposure to sulphuric acid vapour concentrations as high as 0.18 mg/m3. All three workers were diagnosed with NPC within a 5 month period between September 1992, and March 1993. Compared with 19 other healthy workers from the same building, these three workers with NPC had worked significantly longer in this building than had the others (mean (SD) (years): 12.7 (0.6) v 7.4 (4.4); p = 0.01). With an in situ nucleic acid hybridisation and immunostaining method for colocalised Epstein-Barr virus (EBV) and secretory component (SC) protein among biopsy specimens of these three patiente with NPCs, it was found that some tumour cells did not contain EBV and SC protein staining signals. These results indicate that EBV infection is not the only risk factor for NPC and long term exposure to relatively low concentrations of sulphuric acid vapour may be associated with the development of NPC. | - |
dc.publisher | BMJ Publishing Group | - |
dc.relation.ispartof | Occupational and Environmental Medicine | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | nucleic acid; secretory component; sulfuric acid; adult; article; controlled study; Epstein Barr virus; human; human tissue; immunohistochemistry; major clinical study; nasopharynx carcinoma; nucleic acid hybridization; occupational exposure; priority journal; risk factor; Taiwan; telecommunication; tumor biopsy; Human herpesvirus 4 | - |
dc.title | Suspected nasopharyngeal carcinoma in three workers with long term exposure to sulphuric acid vapour | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1136/oem.56.6.426 | - |
dc.identifier.pmid | 10474541 | - |
dc.identifier.scopus | 2-s2.0-0032957884 | - |
dc.relation.pages | 426-428 | - |
dc.relation.journalvolume | 56 | - |
dc.relation.journalissue | 6 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Pathology | - |
crisitem.author.dept | Pathology-NTUH | - |
crisitem.author.dept | Pathology | - |
crisitem.author.orcid | 0000-0002-2414-1487 | - |
crisitem.author.orcid | 0000-0003-3928-1412 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 病理學科所 |
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