https://scholars.lib.ntu.edu.tw/handle/123456789/473764
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Lo W.-C. | en_US |
dc.contributor.author | Cheng P.-W. | en_US |
dc.contributor.author | Wang C.-T. | en_US |
dc.contributor.author | Shueng P.-W. | en_US |
dc.contributor.author | Hsieh C.-H. | en_US |
dc.contributor.author | YIH-LEONG CHANG | en_US |
dc.contributor.author | Liao L.-J. | en_US |
dc.creator | Lo W.-C.;Cheng P.-W.;Wang C.-T.;Shueng P.-W.;Hsieh C.-H.;Yih-Leong Chang;Liao L.-J. | - |
dc.date.accessioned | 2020-03-07T06:56:19Z | - |
dc.date.available | 2020-03-07T06:56:19Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962496768&doi=10.1371%2fjournal.pone.0149346&partnerID=40&md5=76361f4b9955999ed27c0f2299babbf0 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/473764 | - |
dc.description.abstract | Objectives To investigate the effect of radiotherapy (RT) on ultrasound-guided fine needle aspiration (USgFNA) and sonographic characteristics in the assessment of cervical lymph nodes (LNs) in oral squamous cell carcinoma (OSCC) patients after primary treatment. Materials and Methods 88 treated OSCC patients underwent 111 USgFNAs of the neck LNs after US evaluation. Among them, 48 USgFNAs were performed on 40 patients following RT and 63 USgFNAs on 48 patients without previous RT. The results of USgFNA and the US characteristics were compared between these two groups. Results USgFNA had a sensitivity of 88.0%, specificity of 91.4%, positive predictive value (PPV) of 88.0%, negative predictive value (NPV) of 91.4%and accuracy of 90.0%in patients without previous RT, and a sensitivity of 97.1%, specificity of 83.3%, PPV of 94.3%, NPV of 90.9% and accuracy of 93.5%in those with previous neck RT. The ranges of the short-axis and long-axis length were 13.3 ± 8.0 mm (mean ± SD) versus 17.8 ± 9.1 mm, and 18.6 ± 9.0 mm versus 24.4 ± 10.9mm for recurrent LNs frompatients with, versus without, previous RT (both ps < 0.05), respectively. 76.5% (26/34) of the recurrent nodes after RT and 48%(12/25) of the recurrent nodes without previous RT exhibited an irregular margin (p < 0.05). Additionally, irradiated recurrent LNs had a significantly decreased percentage of discernable calcification compared with non-irradiated recurrent nodes (48%versus 20.6%, p < 0.05). Conclusions RT had influence on sonographic characteristics but no influence on USgFNA in diagnosing recurrent LNs in treated OSCC patients. ? 2016 Lo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | - |
dc.publisher | Public Library of Science | - |
dc.relation.ispartof | PLoS ONE | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; aged; Article; calcification; cancer patient; cancer radiotherapy; cervical lymph node; clinical feature; controlled study; diagnostic accuracy; diagnostic test accuracy study; female; fine needle aspiration biopsy; human; lymph node metastasis; major clinical study; male; middle aged; mouth squamous cell carcinoma; predictive value; recurrent disease; sensitivity and specificity; therapy effect; ultrasound; ultrasound guided fine needle aspiration biopsy; clinical trial; endoscopic ultrasound guided fine needle biopsy; Mouth Neoplasms; pathology; sentinel lymph node biopsy; very elderly; Adult; Aged; Aged, 80 and over; Endoscopic Ultrasound-Guided Fine Needle Aspiration; Female; Humans; Male; Middle Aged; Mouth Neoplasms; Sentinel Lymph Node Biopsy | - |
dc.title | The effect of radiotherapy on ultrasound-guided fine needle aspiration biopsy and the ultrasound characteristics of neck lymph nodes in oral cancer patients after primary treatment | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1371/journal.pone.0149346 | - |
dc.identifier.pmid | 26954569 | - |
dc.identifier.scopus | 2-s2.0-84962496768 | - |
dc.relation.pages | e0149346 | - |
dc.relation.journalvolume | 11 | - |
dc.relation.journalissue | 3 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Pathology | - |
crisitem.author.dept | Pathology-NTUH | - |
crisitem.author.dept | Pathology-NTUCC | - |
crisitem.author.orcid | 0000-0001-5309-0554 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
顯示於: | 病理學科所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。