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  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/474419
Title: Application of ultrasound-guided core biopsy to minimize the non-diagnostic results and the requirement of diagnostic surgery in extrapulmonary tuberculosis of the head and neck
Authors: UE-CHEUNG HO 
Chun-Nan Chen 
CHE-YI LIN 
Hsu, Ya-Ching
Chi, Fan-Hsiang
Chou, Chen-Han
TSENG-CHENG CHEN 
CHENG-PING WANG 
PEI-JEN LOU 
JENG-YUH KO 
Hsiao, Tzu-Yu
TSUNG-LIN YANG 
Keywords: Core biopsy;Extrapulmonary tuberculosis;Head and neck;Minimally invasive;Ultrasound
Issue Date: Sep-2016
Publisher: Springer Verlag
Journal Volume: 26
Journal Issue: 9
Start page/Pages: 2999
Source: European Radiology
Abstract: 
Purpose: Head and neck extrapulmonary tuberculosis (ETB) presenting as lymphadenopathy poses a great threat by potentially increasing the deterioration of clinical outcomes. Tissue sampling for diagnostic confirmation of ETB is the only invasive procedure during the entire clinical course. It is, therefore, necessary to establish ETB sampling methods with accuracy and minimal invasiveness. Methods: From 2009 to 2014, consecutive patients suspected of ETB receiving ultrasound-guided core biopsy (USCB), fine needle aspiration (FNA), and open biopsy (OB) were enrolled for comparison. Results: There were 52 cases in the USCB group, 58 cases in the FNA group, and 78 cases in the OB group. For USCB, FNA, and OB groups, the diagnostic rates were 84.6 %, 8.6 %, and 100 % and the positive rates of acid-fast stain were 28.6 %, 0 %, and 37.5 %, respectively. The diagnostic rates of culture were 9.6 %, 0 %, and 50 %, respectively. For head and neck ETB, USCB procedure is timesaving, without leaving poor-healing wounds, scars, and the need for general anaesthesia and hospitalization. Conclusions: This study helps to optimize the ETB sampling method in head and neck based on diagnostic accuracy and minimal invasiveness. USCB can serve as the first-line diagnostic tool for ETB by reducing non-diagnostic results and the need for diagnostic surgery. Key Points: • USCB shows higher diagnostic accuracy of ETB than FNA (84.6 % vs. 8.6 %). • USCB diminishes wound complications caused by surgical intervention for ETB. • USCB avoids general anaesthesia and hospitalization for diagnosing ETB. • USCB saves time and reduces the medical costs of diagnosing ETB. © 2016, European Society of Radiology.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953378416&doi=10.1007%2fs00330-015-4159-4&partnerID=40&md5=7102b3f14a95b6054d2047e6f571f149
https://scholars.lib.ntu.edu.tw/handle/123456789/474419
ISSN: 0938-7994
DOI: 10.1007/s00330-015-4159-4
Appears in Collections:醫學系

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