https://scholars.lib.ntu.edu.tw/handle/123456789/474485
標題: | Association of obstructive sleep apnea and auditory dysfunctions in older subjects | 作者: | Hwang J.-H. Chen J.-C. Hsu C.-J. TIEN-CHEN LIU |
關鍵字: | Auditory dysfunctions; Central obesity; Obstructive sleep apnea; Pitch pattern sequence; Pure-tone averages | 公開日期: | 2011 | 卷: | 144 | 期: | 1 | 起(迄)頁: | 114-119 | 來源出版物: | Otolaryngology - Head and Neck Surgery | 摘要: | Objective. Determine the association between obstructive sleep apnea (OSA) and auditory dysfunction in older subjects. Study Design. Cross-sectional study. Setting. Hospital volunteer helpers undergoing questionnaire, morphometry measurement, auditory examinations, and polysomnography between 2008 and 2009. Subjects and Methods. In total, 224 subjects older than 50 years were randomly sampled for above evaluation and testing. The effects of OSA on the peripheral auditory function, represented by averaged pure-tone threshold of low frequencies (PTA-low) and high frequencies (PTA-high), and central auditory function, shown by pitch pattern sequence (PPS scores), were analyzed. Results. The mean ± SD age was 61.2 ± 6.7 years. OSA was confirmed in 6 of 98 women (6.1%) and 28 of 126 men (22.2%). After adjusting for age, gender, and other variables, OSA did not show a significant positive association with PTA-low or PTA-high for all subjects. Conversely, there was a significant negative association between OSA and PPS scores for all subjects, even after adjusting for age, gender, and other variables. When OSA and central obesity together were taken into account in the multivariate linear regression analysis, OSA still showed significant association with PPS score for all subjects. Conclusion. OSA is independently associated with poorer central auditory function in older subjects. ? American Academy of Otolaryngology - Head and Neck Surgery Foundation 2011. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-79959624574&doi=10.1177%2f0194599810390859&partnerID=40&md5=5d2813551cb8888de469b5ce26d41999 https://scholars.lib.ntu.edu.tw/handle/123456789/474485 |
ISSN: | 0194-5998 | DOI: | 10.1177/0194599810390859 | SDG/關鍵字: | adult; article; audiometry; cross-sectional study; disease association; female; hearing; hearing disorder; human; major clinical study; male; morphometrics; obesity; polysomnography; questionnaire; sleep apnea syndrome; comparative study; hearing; hearing disorder; middle aged; pathophysiology; physiology; pure tone audiometry; retrospective study; risk factor; sleep apnea syndrome; Audiometry, Pure-Tone; Cross-Sectional Studies; Female; Hearing; Hearing Disorders; Humans; Male; Middle Aged; Polysomnography; Questionnaires; Retrospective Studies; Risk Factors; Sleep Apnea, Obstructive |
顯示於: | 醫學系 |
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