https://scholars.lib.ntu.edu.tw/handle/123456789/474996
標題: | Risk factors for recurrent bacteremia in adult patients with nontyphoid salmonellosis | 作者: | RON-BIN HSU Chen R.J. Chu S.-H. |
關鍵字: | Bacteremia; Nontyphoid Salmonella; Recurrence | 公開日期: | 2004 | 出版社: | Lippincott Williams and Wilkins | 卷: | 328 | 期: | 6 | 起(迄)頁: | 315-318 | 來源出版物: | American Journal of the Medical Sciences | 摘要: | Background: This study sought to find the risk factors for recurrent bacteremia in adult patients with non-typhoid salmonellosis. Method Retrospective chart review. Result: Between September 1984 and December 2003, 235 adult (age ? 18 years old) patients with bacteremia with nontyphoid salmonellosis were admitted to our hospital. Among them, 130 patients (55%) had immunodeficiency, 31 patients (13%) had systemic lupus erythematosus, 26 patients (11%) had hematologic malignancies, 50 patients (21%) had solid organ cancers, and 39 patients (17%) had endovascular infections. Thirty-seven patients had recurrent bacteremia during the study period. Both univariate and multivariate analysis showed that immunodeficiency was the only predictor of recurrent bacteremia (odds ratio, 2.79; P = 0.013). The overall hospital mortality rate was 26%: 8% for patients with recurrent bacteremia and 29% for patients without recurrence. The independent risk factors of hospital death were old age, not recurrent infection, and solid organ cancers. Conclusion: Old age, systemic lupus erythematosus, malignancies, and immunodeficiency were common in adult patients with nontyphoid Salmonella bacteremia. The incidence of recurrent bacteremia was 16%. Immunodeficiency predisposed patients to recurrent bacteremia. Recurrent bacteremia was associated with a lower hospital mortality rate, however. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-10644271580&doi=10.1016%2fS0002-9629%2815%2933940-9&partnerID=40&md5=ed53a285a3f23e2510d6da0dace0e3db https://scholars.lib.ntu.edu.tw/handle/123456789/474996 |
ISSN: | 0002-9629 | DOI: | 10.1016/S0002-9629(15)33940-9 | SDG/關鍵字: | adult; age distribution; aged; article; bacteremia; controlled study; death; female; human; immune deficiency; major clinical study; male; mortality; multivariate analysis; recurrent disease; retrospective study; risk factor; Salmonella; salmonellosis |
顯示於: | 醫學系 |
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