https://scholars.lib.ntu.edu.tw/handle/123456789/475341
標題: | Lower airway anomalies in children with CATCH 22 syndrome and congenital heart disease | 作者: | CHING-CHIA WANG SHYH-JYE CHEN EN-TING WU CHUN-AN CHEN SHUENN-NAN CHIU MING-TAI LIN FRANK LEIGH LU SHU-CHIEN HUANG MEI-HWAN WU JOU-KOU WANG |
公開日期: | 2013 | 卷: | 48 | 期: | 6 | 起(迄)頁: | 587-591 | 來源出版物: | Pediatric Pulmonology | 摘要: | Objective CATCH 22 syndrome is a medical acronym for multiple abnormalities, especially cardiac defect. The patients with congenital heart disease (CHD) usually have more complicated post-surgery course. Methods We reviewed 4-year experience in our hospital to define the lower airway anomalies and the clinical implications in patients with CATCH 22 syndrome and CHD. From 2004 to 2007, 18 patients who underwent computed tomography for planning of cardiovascular treatment were enrolled. Detection of airway anomalies were performed on computed tomography. Results Characteristic dysmorphic facial features were noted in 8 out of 18 patients (44%). Ten patients (55.6%) had mild to moderate tracheal or bronchial stenosis. Five patients (28%) had tracheomalacia or bronchomalacia. Comparing to control group, patients received the first major surgery with a median hospital stays of 42 days in study group had a significantly longer hospital stay (42 vs. 16, P = 0.005) and longer duration of ventilator usage (16 vs. 4, P = 0.014). The difference of the mean position of the carina on computed tomography image between study groups and control groups was about three-quarters of a vertebral body height (P < 0.05). Conclusions: Patients with CATCH 22 syndrome and CHD had a shorter length of trachea compared to that of the age-matched similar CHD. The incidence of associated lower airway anomalies in CHD children with CATCH 22 syndrome was higher. It may lead to longer time of ventilator support after surgery as well as total hospital stays than those of CHD without CATCH 22 syndrome. Pediatr Pulmonol. 2013; 48:587-591. ? 2012 Wiley Periodicals, Inc. Copyright ? 2012 Wiley Periodicals, Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84878280850&doi=10.1002%2fppul.22674&partnerID=40&md5=2ecf50aec54896b13fd2fc3d128ccb93 https://scholars.lib.ntu.edu.tw/handle/123456789/475341 |
ISSN: | 8755-6863 | DOI: | 10.1002/ppul.22674 | SDG/關鍵字: | arterial trunk; article; bronchomalacia; bronchus stenosis; cardiovascular malformation; CATCH 22 syndrome; child; clinical article; computer assisted tomography; congenital heart disease; controlled study; disease association; facies; Fallot tetralogy; female; great vessels transposition; heart ventricle septum defect; human; infant; length of stay; lower respiratory tract; male; newborn; preschool child; priority journal; pulmonary valve atresia; respiratory tract malformation; retrospective study; tracheomalacia; vertebra body; Abnormalities, Multiple; Bronchomalacia; Case-Control Studies; Child, Preschool; DiGeorge Syndrome; Female; Heart Defects, Congenital; Humans; Incidence; Infant; Infant, Newborn; Male; Prognosis; Retrospective Studies; Tomography, X-Ray Computed; Tracheomalacia |
顯示於: | 醫學系 |
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