https://scholars.lib.ntu.edu.tw/handle/123456789/479507
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | VIN-CENT WU | en_US |
dc.contributor.author | SHIH-CHIEH CHUEH | en_US |
dc.contributor.author | Chang H.-W. | en_US |
dc.contributor.author | LIAN-YU LIN | en_US |
dc.contributor.author | KAO-LANG LIU | en_US |
dc.contributor.author | YEN-HUNG LIN | en_US |
dc.contributor.author | YI-LWUN HO | en_US |
dc.contributor.author | WEI-CHOU LIN | en_US |
dc.contributor.author | SHUO-MENG WANG | en_US |
dc.contributor.author | KUO-HOW HUANG | en_US |
dc.contributor.author | KUAN-YU HUNG | en_US |
dc.contributor.author | Kao T.-W. | en_US |
dc.contributor.author | SHUEI-LIONG LIN | en_US |
dc.contributor.author | RUOH-FANG YEN | en_US |
dc.contributor.author | YUNG-MING CHEN | en_US |
dc.contributor.author | Hsieh B.-S. | en_US |
dc.contributor.author | KWAN-DUN WU | en_US |
dc.creator | Wu K.-D.;Hsieh B.-S.;Chen Y.-M.;Yen R.-F.;Lin S.-L.;Kao T.-W.;Hung K.-Y.;Huang K.-H.;Wang S.-M.;Lin W.-C.;Ho Y.-L.;Lin Y.-H.;KAO-LANG LIU;Lin L.-Y.;Chang H.-W.;Chueh S.-C.;Wu V.-C. | - |
dc.date.accessioned | 2020-03-27T02:03:42Z | - |
dc.date.available | 2020-03-27T02:03:42Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0272-6386 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/479507 | - |
dc.description.abstract | Background: Autonomous secretion of aldosterone in patients with primary aldosteronism increases glomerular filtration rate and causes kidney damage. The influence of a mild decrease in kidney function on residual hypertension after adrenalectomy is unexplored. Study Design: Nonconcurrent prospective study. Setting & Participants: The study was based on the Taiwan Primary Aldosteronism Investigation (TAIPAI) database. 150 patients (61 men; overall mean age, 47.2 ± 11.6 years) with a diagnosis of aldosterone-producing adenoma had undergone unilateral adrenalectomy at National Taiwan University Hospital from July 1999 to January 2007. Predictor: Presurgery estimated glomerular filtration rate (eGFR). Outcomes & Measurements: Residual hypertension after adrenalectomy, defined either as less than 75% of recorded blood pressure measurements with systolic blood pressure less than 140 mm Hg and diastolic blood pressure less than 90 mm Hg or requiring antihypertensive medications during the first year after surgery. Results: Before surgery, 27 (18%), 72 (48%), and 51 (34%) patients had moderately to severely decreased (<60 mL/min/1.73 m2), mildly decreased (60 ? eGFR < 90 mL/min/1.73 m2), or nondecreased eGFR (?90 mL/min/1.73 m2), respectively. After surgery, 16 (59.3%), 29 (40.3%), and 10 (19.3%) patients in each category had postsurgery residual hypertension. Compared with patients without decreased eGFR before surgery, adjusted odds ratios for postsurgery residual hypertension were 2.7 (95% confidence interval, 1.03 to 7.0; P = 0.04) and 2.8 (95% confidence interval, 1.05 to 9.3) for mildly and moderately to severely decreased eGFR, respectively. Limitations: Arbitrary definition for residual hypertension. Conclusions: Two-thirds of patients with aldosterone-producing adenoma were cured of hypertension by means of unilateral adrenalectomy. Kidney function impairment, even mild, appears to be associated with a high incidence of postsurgery residual hypertension. ? 2009 National Kidney Foundation, Inc. | en_US |
dc.relation.ispartof | American Journal of Kidney Diseases | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | antihypertensive agent; captopril; adrenal cortex adenoma; adrenalectomy; adult; aldosterone producing adenoma; article; blood pressure measurement; controlled study; diastolic blood pressure; disease association; disease severity; female; glomerulus filtration rate; human; hypertension; kidney dysfunction; kidney function; major clinical study; male; monotherapy; postoperative period; primary hyperaldosteronism; prospective study; redisual hypertension; residual hypertension; surgical technique; systolic blood pressure; Taiwan; university hospital; Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Creatinine; Female; Glomerular Filtration Rate; Humans; Hyperaldosteronism; Hypertension; Kidney; Kidney Function Tests; Male; Middle Aged; Odds Ratio; Retrospective Studies; Severity of Illness Index | - |
dc.title | Association of Kidney Function With Residual Hypertension After Treatment of Aldosterone-Producing Adenoma | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1053/j.ajkd.2009.06.014 | - |
dc.identifier.pmid | 19628318 | - |
dc.identifier.scopus | 2-s2.0-70349236911 | - |
dc.relation.pages | 665-673 | en_US |
dc.relation.journalvolume | 54 | en_US |
dc.relation.journalissue | 4 | en_US |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Medicine-NTUCC | - |
crisitem.author.dept | Urology | - |
crisitem.author.dept | Urology-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Master's Program in Smart Medicine and Health Informatics (SMARTMHI) | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Medical Imaging-NTUH | - |
crisitem.author.dept | Medical Imaging-NTUCC | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Pathology | - |
crisitem.author.dept | Pathology-NTUH | - |
crisitem.author.dept | Urology-NTUH | - |
crisitem.author.dept | Urology | - |
crisitem.author.dept | Urology-NTUHHC | - |
crisitem.author.dept | Urology-NTUHBH | - |
crisitem.author.dept | Urology | - |
crisitem.author.dept | Urology-NTUH | - |
crisitem.author.dept | Surgical Oncology-NTUCC | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Physiology | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Integrated Diagnostics and Therapeutics-NTUH | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Nuclear Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Geriatrics and Gerontology-NTUH | - |
crisitem.author.dept | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-7935-0991 | - |
crisitem.author.orcid | 0000-0002-0713-4904 | - |
crisitem.author.orcid | 0000-0001-7505-6429 | - |
crisitem.author.orcid | 0000-0003-4100-8909 | - |
crisitem.author.orcid | 0000-0001-8153-1441 | - |
crisitem.author.orcid | 0000-0002-8936-9570 | - |
crisitem.author.orcid | 0000-0003-2857-3479 | - |
crisitem.author.orcid | 0000-0003-2090-1757 | - |
crisitem.author.orcid | 0000-0002-0989-0578 | - |
crisitem.author.orcid | 0000-0003-3472-5512 | - |
crisitem.author.orcid | 0000-0002-1041-5571 | - |
crisitem.author.orcid | 0000-0003-1648-6482 | - |
crisitem.author.orcid | 0000-0002-9241-1258 | - |
crisitem.author.orcid | 0000-0002-3339-1509 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | International College | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
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