https://scholars.lib.ntu.edu.tw/handle/123456789/480077
標題: | Skin and soft-tissue infection caused by non-tuberculous mycobacteria in Taiwan, 1997-2008 | 作者: | Chen H.-Y. CHUNG-YU CHEN CHUN-TA HUANG SHENG-YUAN RUAN Chou C.H. Lai C.C. Liao C.H. Tan C.K. YU-TSUNG HUANG CHONG-JEN YU PO-REN HSUEH |
公開日期: | 2011 | 卷: | 139 | 期: | 1 | 起(迄)頁: | 121-129 | 來源出版物: | Epidemiology and Infection | 摘要: | The aim of this study was to investigate the clinical, microbiological, and pathological characteristics and the outcomes of skin and soft-tissue infection (SSTI) caused by non-tuberculous mycobacteria (NTM). Medical records of 50 patients with SSTI caused by NTM identified from 2005 to 2008 and 63 patients previously reported in a medical centre from 1997 to 2004 were reviewed. The annual incidence (per 100 000 outpatients and in-patients) ranged from 0.57 in 2005, 0.38 in 2007, to 1.1 in 2008, with an average of 0.62/100 000. From 1997 to 2008, the average incidence was 1.39/100 000 patients. The average annual incidence of SSTI caused by NTM was 0.62/100 000 outpatients and in-patients during 2005 and 2008. Of the total of 113 patients identified during the 12-year period, patients infected with Mycobacterium fortuitum and M. marinum were younger than those infected with M. avium-intracellulare complex (MAC) (36 and 44 years vs. 55 years, P=0004 and P=0056, respectively), and were more likely to have previous invasive procedures than those infected with MAC and M. abscessus (81.8% and 72.0% vs. 27.8% and 54.8%, P=0.007), and less likely to have associated immunosuppression (9.1% and 24% vs. 66.7% and 45.2%, P=0.006). Granuloma was more often observed in immunocompetent patients (60.1% vs. 40%, P=0.019), and in M. marinum-infected specimens (78.3%). There were significant differences in the demographic and clinical features of patients with NTM SSTI, including immunosuppression, trauma experience, and depth of tissue infections. ? 2010 Cambridge University Press. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/480077 | ISSN: | 0950-2688 | DOI: | 10.1017/S0950268810001603 | SDG/關鍵字: | amikacin; ciprofloxacin; clarithromycin; cotrimoxazole; ethambutol; imipenem; minocycline; moxifloxacin; quinoline derived antiinfective agent; rifabutin; rifampicin; antiinfective agent; adult; age distribution; aged; article; bacteremia; clinical feature; demography; female; granuloma; histopathology; hospital patient; human; immune deficiency; incidence; major clinical study; male; medical record review; microbiological examination; Mycobacterium abscessus; Mycobacterium fortuitum; Mycobacterium intracellulare avium; Mycobacterium marinum; osteomyelitis; outcome assessment; outpatient; skin abscess; skin infection; soft tissue infection; Taiwan; adolescent; atypical mycobacteriosis; atypical Mycobacterium; bacterial skin disease; child; classification; infant; isolation and purification; microbiology; middle aged; preschool child; retrospective study; soft tissue infection; Taiwan; time; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Child, Preschool; Female; Humans; Infant; Male; Middle Aged; Mycobacteria, Atypical; Mycobacterium Infections, Atypical; Retrospective Studies; Skin Diseases, Bacterial; Soft Tissue Infections; Taiwan; Time Factors; Young Adult |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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