https://scholars.lib.ntu.edu.tw/handle/123456789/480108
標題: | Epidemiology of bloodstream infections in patients with haematological malignancies with and without neutropenia | 作者: | Chen C.-Y. WOEI TSAY JIH-LUH TANG HWEI-FANG TIEN YEE-CHUN CHEN SHAN-CHWEN CHANG PO-REN HSUEH |
公開日期: | 2010 | 卷: | 138 | 期: | 7 | 起(迄)頁: | 1044-1051 | 來源出版物: | Epidemiology and Infection | 摘要: | All bacterial isolates from 7058 patients admitted to haemato-oncology wards at National Taiwan University Hospital between 2002 and 2006 were characterized. In total 1307 non-duplicate bloodstream isolates were made from all patients with haematological malignancy; 853 (65%) of these were from neutropenic patients. Gram-negative bacteria predominated (60%) in neutropenic isolates with Escherichia coli (12%), Klebsiella pneumoniae (10%), Acinetobacter calcoaceticus-baumannii complex (6%), and Stenotrophomonas maltophilia (6%) the most frequent. Coagulase-negative staphylococci (19%) and Staphylococcus aureus (4%) were the most common Gram-positive pathogens. Resistance to ciprofloxacin was found in 50% of E. coli and 20% of K. pneumoniae isolates from neutropenic patients. Extensively drug-resistant A. calcoaceticus-baumannii complex and vancomycin-resistant enterococci were also found during the study period. Emerging antimicrobial resistant pathogens are an increasing threat to neutropenic cancer patients. Copyright ? 2009 Cambridge University Press. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/480108 | ISSN: | 0950-2688 | DOI: | 10.1017/S0950268809991208 | SDG/關鍵字: | amikacin; aztreonam; cefepime; cefotaxime; ciprofloxacin; colistin; gentamicin; imipenem; levofloxacin; meropenem; moxifloxacin; sultamicillin; timentin; vancomycin; Acinetobacter baumannii; Acinetobacter calcoaceticus; acute granulocytic leukemia; acute lymphoblastic leukemia; antibiotic prophylaxis; antibiotic resistance; aplastic anemia; article; bacterium isolation; bloodstream infection; cancer patient; Candida albicans; Candida parapsilosis; Candida tropicalis; chronic lymphatic leukemia; chronic myeloid leukemia; Enterobacter cloacae; Enterococcus faecalis; Enterococcus faecium; Escherichia coli; febrile neutropenia; hematologic malignancy; hospital admission; human; Klebsiella oxytoca; Klebsiella pneumoniae; major clinical study; mortality; multiple myeloma; myelodysplastic syndrome; nonhodgkin lymphoma; oncology ward; Proteus mirabilis; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis; Stenotrophomonas maltophilia; Acinetobacter baumannii; Acinetobacter Infections; Bacteremia; Escherichia coli Infections; Gram-Negative Bacterial Infections; Hematologic Neoplasms; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Neutropenia; Staphylococcal Infections; Stenotrophomonas maltophilia; Taiwan |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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