https://scholars.lib.ntu.edu.tw/handle/123456789/481042
標題: | The severity of initial acute kidney injury at admission of geriatric patients significantly correlates with subsequent in-hospital complications | 作者: | CHIA-TER CHAO Tsai H.-B. CHIA-YI WU YU-FENG LIN NIN-CHIEH HSU JIN-SHING CHEN KUAN-YU HUNG |
公開日期: | 2015 | 出版社: | Nature Publishing Group | 卷: | 5 | 起(迄)頁: | 13925 | 來源出版物: | Scientific Reports | 摘要: | Acute kidney injury (AKI) is associated with higher hospital mortality. However, the relationship between geriatric AKI and in-hospital complications is unclear. We prospectively enrolled elderly patients (? 65 years) from general medical wards of National Taiwan University Hospital, part of whom presented AKI at admission. We recorded subsequent in-hospital complications, including catastrophic events, incident gastrointestinal bleeding, hospital-associated infections, and new-onset electrolyte imbalances. Regression analyses were utilized to assess the associations between in-hospital complications and the initial AKI severity. A total of 163 elderly were recruited, with 39% presenting AKI (stage 1: 52%, stage 2: 23%, stage 3: 25%). The incidence of any in-hospital complication was significantly higher in the AKI group than in the non-AKI group (91% vs. 68%, p < 0.01). Multiple regression analyses indicated that elderly patients presenting with AKI had significantly higher risk of developing any complication (Odds ratio [OR] = 3.51, p = 0.01) and new-onset electrolyte imbalance (OR = 7.1, p < 0.01), and a trend toward more hospital-associated infections (OR = 1.99, p = 0.08). The risk of developing complications increased with higher AKI stage. In summary, our results indicate that initial AKI at admission in geriatric patients significantly increased the risk of in-hospital complications. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941248364&doi=10.1038%2fsrep13925&partnerID=40&md5=6240c3de0e8275d6b9e528707bb0763a https://scholars.lib.ntu.edu.tw/handle/123456789/481042 |
ISSN: | 2045-2322 | DOI: | 10.1038/srep13925 | SDG/關鍵字: | Acid-Base Imbalance; Acute Kidney Injury; aged; comorbidity; female; geriatric assessment; hospital admission; hospital mortality; human; incidence; male; outcome assessment; risk factor; severity of illness index; Taiwan; very elderly; Acid-Base Imbalance; Acute Kidney Injury; Aged; Aged, 80 and over; Comorbidity; Female; Geriatric Assessment; Hospital Mortality; Humans; Incidence; Male; Patient Admission; Patient Outcome Assessment; Risk Factors; Severity of Illness Index; Taiwan |
顯示於: | 醫學系 |
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