https://scholars.lib.ntu.edu.tw/handle/123456789/481538
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | KE-CHENG CHEN | en_US |
dc.contributor.author | JANG-MING LEE | en_US |
dc.creator | Chen K.-C.;Jang-Ming Lee | - |
dc.date.accessioned | 2020-03-31T03:59:15Z | - |
dc.date.available | 2020-03-31T03:59:15Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 2072-1439 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045221827&doi=10.21037%2fjtd.2018.03.139&partnerID=40&md5=ea604b4b544ec61007dd5fcd6e851f04 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/481538 | - |
dc.description.abstract | Background: With the aid of electromagnetic navigation bronchoscopy (ENB), it has become possible to approach peripheral lung tumors from the airway. Meanwhile, local ablation using photodynamic therapy (PDT) has shown increasing promise in the realm of lung cancer treatment. The purpose of this study was to explore an alternative ablation method using PDT with SuperDimension ENB localization in a hybrid operating theater. Methods: Our study includes patients with primary or metastatic lung cancer who underwent PDT via ENB in the hybrid operating room (OR) of National Taiwan University Hospital between January 2016 and January 2017. ENB with the SuperDimension Navigation System (7th edition) was performed before PDT ablation to localize the target lesions. PDT ablation was performed with the assistance of intraoperative Dyna-computed tomography (Dyna-CT). Tumor response was evaluated by CT 3 months after the procedure. Results: Three patients underwent lung interstitial PDT via the aid of ENB during the study period. The mean size of the nodules was 21.3 mm. The mean navigation time was 14.3 minutes. In all cases, the target pulmonary nodule was ablated by PDT successfully. No major procedure-related complications occurred. One patient suffered from skin hypersensitivity one month after the procedure. The follow-up CT showed significant tumor shrinkage for all the patients. They were all discharged without incident a few days after the procedure as scheduled. Conclusions: PDT with SuperDimension ENB guidance in the hybrid OR is a novel and feasible approach to control peripheral lung malignancy. ? Journal of Thoracic Disease. | en_US |
dc.language.iso | en | en_US |
dc.publisher | AME Publishing Company | en_US |
dc.relation.ispartof | Journal of Thoracic Disease | en_US |
dc.subject | Electromagnetic navigation bronchoscopy (ENB); Peripheral-type lung malignancy; Photodynamic therapy (PDT); SuperDimension | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; aged; Article; bronchoscopy; clinical article; computer assisted tomography; electromagnetic navigation bronchoscopy; electromagnetism; female; follow up; hospital discharge; human; lung cancer; lung nodule; male; middle aged; photodynamic therapy; postoperative complication; prospective study; skin allergy; tumor ablation; tumor volume | - |
dc.title | Photodynamic therapeutic ablation for peripheral pulmonary malignancy via electromagnetic navigation bronchoscopy localization in a hybrid operating room (OR): A pioneering study | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.21037/jtd.2018.03.139 | - |
dc.identifier.scopus | 2-s2.0-85045221827 | - |
dc.relation.pages | S725-S730 | en_US |
dc.relation.journalvolume | 10 | en_US |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.orcid | 0000-0001-6330-0674 | - |
crisitem.author.orcid | 0000-0001-9727-227X | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學系 |
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