https://scholars.lib.ntu.edu.tw/handle/123456789/484027
標題: | A nationwide survey of adherence to analgesic drugs among cancer patients in Taiwan: prevalence, determinants, and impact on quality of life | 作者: | Chou, Wen Chi Chen, Jen Shi Hung, Chia Yen Lu, Chang Hsien YU-YUN SHAO Chiou, Tzeon Jye Sung, Yung Chuan Rau, Kun Ming Yen, Chia Jui Yeh, Su Peng Liu, Ta Chih Wu, Ming Fang Lee, Ming Yang Yu, Ming Sun Hwang, Wen Li Lai, Pang Yu Chang, Cheng Shyong Hsieh, Ruey Kuen |
關鍵字: | Adherence | Cancer | Pain | Predictive factor | Quality of life;Adherence; Cancer; Pain; Predictive factor; Quality of life | 公開日期: | 1-八月-2019 | 卷: | 27 | 期: | 8 | 來源出版物: | Supportive Care in Cancer | 摘要: | © 2018, Springer-Verlag GmbH Germany, part of Springer Nature. Purpose: Poor adherence to analgesic drugs is one of the most common barriers to adequate pain management. This prospective, cross-sectional, patient-oriented observational study aimed to explore the adherence rate, clinical factors, and impact of adherence to analgesic drugs on the quality of life (QoL) among cancer outpatients in Taiwan. Methods: Eight hundred ninety-seven consecutive adult outpatients with cancer who had reported tumor pain and received regular analgesic drug treatment were enrolled from 16 medical centers across Taiwan. The Brief Pain Inventory was used to assess pain intensity and QoL. Morisky’s four-item medication adherence scale was used to assess adherence to analgesic drugs. Clinical factors possibly associated with good adherence to analgesic drugs were analyzed using multivariate logistic regression analyses. Results: Of the 897 patients, 26.9% met criteria for the good, 35.5% for the moderate, and 37.6% for the poor adherence groups. The good adherence group had significantly better QoL outcomes than the moderate and poor adherence groups (all p < 0.05). Age ≥ 50 years, head and neck or hematological malignancies, cancer-related pain, patients who agreed or strongly agreed that the side effects of analgesic drugs were tolerable, and patients who disagreed or strongly disagreed that the dosing schedule could be flexibly self-adjusted to deal with the actual pain were predictors of good adherence to analgesic drugs. Conclusions: Awareness of the clinical factors associated with adherence to analgesic drugs may help clinicians to identify cancer patients at a greater risk of non-adherence, reinforce optimal pain management, and improve the QoL by enhancing adherence to pain medications. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/484027 | ISSN: | 09414355 | DOI: | 10.1007/s00520-018-4599-x | SDG/關鍵字: | analgesic agent; analgesic agent; adult; aged; analgesia; Article; breast cancer; Brief Pain Inventory; cancer pain; cancer patient; clinical assessment; cross-sectional study; digestive system cancer; drug tolerability; female; head and neck cancer; health survey; hematologic malignancy; human; major clinical study; male; malignant neoplasm; medication compliance; middle aged; Morisky Medication Adherence Scale; multicenter study; observational study; outcome assessment; outpatient care; pain intensity; patient compliance; prevalence; priority journal; prospective study; quality of life; Taiwan; thorax cancer; treatment indication; unspecified side effect; cancer pain; medication compliance; neoplasm; outpatient; pathophysiology; prevalence; quality of life; questionnaire; statistics and numerical data; Adult; Aged; Analgesics; Cancer Pain; Cross-Sectional Studies; Female; Humans; Male; Medication Adherence; Middle Aged; Neoplasms; Outpatients; Prevalence; Prospective Studies; Quality of Life; Surveys and Questionnaires; Taiwan |
顯示於: | 腫瘤醫學研究所 |
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