Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial

Martin M;Holmes F.A;Ejlertsen B;Delaloge S;Moy B;Iwata H;Von Minckwitz G;Chia S.K.L;Mansi J;Barrios C.H;Gnant M;Toma?Evi? Z;Denduluri N;?Eparovi? R;Gokmen E;Bashford A;Ruiz Borrego M;Kim S.-B;Jakobsen E.H;Ciceniene A;Inoue K;Overkamp F;Heijns J.B;Armstrong A.C;Link J.S;Joy A.A;Bryce R;Wong A;Moran S;Yao B;Xu F;Auerbach A;Buyse M;Chan A;Harvey V;Tomek R;Robert N.J;Gore I;Jr;Smith J.W;Ii, Masuda N;Di Sean Kendall S;Harker W.G;Petrakova K;Guerrero Zotano A;Simon A.R;Konstantinovic Z.N;Iannotti N.O;Tassone P;Rodriguez G.I;J??Ez Martinez N;Crespo Massieu C;Smickoska S;Somali I;Yilmaz U;Alonso M.G;Rosales A.M;Cold S;Knoop A.S;Patt D;Hellerstedt B.A;Morales Murillo S;Mayer I.A;Means-Powell J.A;Hui R;Senecal F.M;De Boer R.H;Shen Z;Luczak A.A;Chui J.W.Y;Tsang J.W.-H;Lang I;Rai Y;Hozumi Y;Ten Tije A.J;Bhandari M;Osborne C.R.C;Ohtani S;Higaki K;Watanabe K;Taguchi K;Takahashi M;Filipovic S;Hansen V.L;Rao V.P;Gupta M;Petrov P;Coudert B;Vojnovic Z;Polya Z;Miyaki T;Yamamoto N;Brincat S;Lesniewski-Kmak K;Chmielowska E;Birhiray R.E;Citron M.L;Papish S.W;Berry W.R;Langkjer S.T;Garcia S?Enz J.A;Arance A.M;Efrat N;Sarosiek T;Grzeda L;Manalo Y;Smith J.C;Vaziri I;Healey T;Rahim Y;Luk C;Dingle B;Franco S;Sorensen P.G;Anand A;Khan S;Fountzilas G;Aogi K;Shimizu S;Mikulova M;Spanik S;Somer R.A;Flynn P.J;Coward J;Mainwaring P;Jerusalem G;Segura-Ojezzar C;Levy C;Delozier T;Khayat D;Coleman R.E;Rolles M.J;Maisano R;Nardi M;Ito Y;Yumuk P.F;Basaran G;Serdar Turhal N;Wilkinson M.J;Green N.B;Sidrys A.P;Hallmeyer S;Testori D.J;Sridhar S;Chang J;Sun Q;Jara-Sanchez C;Rubio X;Garrido M.L;De La Haba Rodriguez J.R;Perello Martorell A;Avelia Mestre A;Rifa Ferrer J;Del Barco Berron S;Nagy Z;Tanaka M;Im Y.-H;Carroll R.R;Dickerson L.C;Mace J.R;Rivera R;Klein L.M;Ruxer R;Wilks S.T;Kotasek D;Popov V;Taskova V;Marinova-Venkova V;Timcheva C;Desbiens C;Ayoub J.-P;Grenier D;Marschner N;Tesch H;Lueck H.-J;Janssen J;Schwaner I;Wahlstrom S;Brix E.H;Vallentin S;Kristensen D;Andreeva A;Glavicic V;Calvo Plaza I;Anton Torres A;Veyret C;Bergerat J.-P;Bourbouloux E;Ella W.A;Algurafi H;Robinson A;Kim S.J;Taguchi T;Juozaityte E;Madretsma S;Radema S;Czerniawska-Meier M;Rogowski W;Wagnerova M;Richards D.A;Tan-Chiu E;Vasileios A;Henderson C.A;Holden V.R;Wang X;Tong Z;Yang J;Gonzalez M.E;Rezai M;Hackmann J;De Due?As E.M;De Las Heras B.B;Dourthe L.M;Chocteau-Bouju D;Bougnoux P;Kakolyris S;Kalofonos H;Pectasidis D;Ng T.Y;Pajkos G;Somogyine E.E;Tonini G;Giuffrida D;Takao S;Ishitobi M;Inaji H;Tokuda Y;Wozniak K;Lungulescu D;Yen-Shen Lu;Chang K.-J;Hill J;Croot C.C;Dekker A;Belman N.D;Conde M;Michaelson R.A;Kemmer K;Chui S;Luoh S.-W;Nahum K;Greenspan A.R;Nichols J.C;Encarnacion C.A;Niederman T.M.J;Lee T;Alexander R;Gordon R;Tomova A;Rauch D;Popescu R.A;Rojas G.A;Vanasek J;Neunhoeffer T;Barinoff J;Graffunder G;Wolfgang A;Bojko P;Heinrich B;Von Der Assen A;Antonovic B.J;Adrian L;Ramos Vazquez M;Gonzalez Santiago S;Dieras V;Bishop J.M;Perren T.J;Varthalitis I;Mavroudis D;Georgoulias V;Chow L.W.C;Yau C.C.T;Liang R.H.-S;Pik? B;W?Ber A;Kaufman B;Drumea K;Nuzzo F;De Matteis A;Nuzzo F;Carteni G;Tokunaga E;Ishida M;Ohno S;Sato N;Kuroi K;Nishimura R;Watanabe J;Choi Y.J;Park K.H;Wojtukiewicz M;Jassem J;Loman N;Askoy S;Altundag M.K;Saip P;Ali M.A;Wade J.L;Iii, Chien A.J;Brandt D;Novik Y;Jani C;Rice R.L;Gaffar Y.A.R;Keaton M.R;Bajaj R;Kimmick G;Campbell D;De Boer R.H;Turnquest T;Lucas S;Dube P;Xu B;Schilling J;Apel K;Sorensen P.G;Vestlev P.M;Jensen B.B;Haahr V;Lescure A.R;Grana Suarez B;Saura Manich C;Jacquin J.-P;Samreen A;Boiangiu I;Dank M;Falci C;Jirillo A;Cinieri S;Ueno T;Sato F;Yamashiro H;Sugie T;Lee K.S;Ro J.S;Park I.H;Bustam A.Z;Suszko-Kazarnowicz M;Piktel A;Krzemieniecki K;Iorga P.G;Yap Y.S;Kakalejcik M;Sevinc A;Ozguroglu M;Chen S.-C;Greenberg R.H;Eisemann A.D;Droder R;Abbasi M.R;Vaysburd M;Caldera H.J;Haley B.B;Robin E;Inhorn R.C;Hufnagel D;Kenyon P.D;Spremulli E;Silverman P;Jain S;Weigand R;Mebis J;Koynova T;Lesperance B;Prausova J;Kohne C.-H;Schneeweiss A;Jackisch C;Fuxius S;Cubedo Cervera R;Urruticoechea Ribate A;Pernas Simon S;Valero Gallego J;Arcusa Lanza A;Del Pilar Alvarez M;Florian Gerico J;Cany L;Stebbing J;Labudovic D;Gugic D;Vrbanec D;Roila F;Barni S;Bidoli P;Mukai H;Bermudez V;Eniu A;Mirtsching B.C;Ibrahim E;Trey J;Hergenroeder P.F;Mahmood A;Gonzalez A;Kaplan E.H;Ban S;Patel D;Clowney B;Hoelzer K;Schwartz G.H;Salkeni M;Abraham J;Narula S;Jabboury K;Mocharnuk R.S;Mcdonough R.H;Sikes D.H;Kawanchi R.H;Schlabach L;Mccachren S.S;Jr;Cosgriff T.M;Dreisbach L;Demichele A;Pawl L;Lucas J;Shinn L.C;Alkhouri N;Monga M;Lindquist D.L;Anderson T.C;Khurshid H;Witherby S;Erickson N;Traynor A;Bose R;Pluard T.J;Jones M.C;Prakash S;Volterra F;Capo G;Flaherty L.E;Gartner E;Baidas S;Okazaki I;Nguyen B;Rakowski T;Oliff I;Leach J.W;Anderson D;Kubiak K;Tsai M;Vroman P;Deleu I;Lybaert W;Borms M;Couture F;Wilson J.J;Hunt G;Holland D.R;Mingrone W;Wang S;Liu D;Jiang Z;Benesova V;Smakal M;Garnolova P;Vesper A.-S;Neumann M;Janni W;Liedtke C;Fischer D;Grischke E.-M;Seeger D;Moebus V;Prechtl A;Carlos Camara Toral J;Sanchez Munoz A;Gonzalez Jimenez S;Cassinello Espinosa J;Cirauqui B;Margeli Vila M;Batista Lopez N;Chacon Lopez-Muniz J.I;De La Cruz Mora M.A;Mailliez A;Vanlemmens L;Pouessel D;Espie M;Conibear J;Roylance R;Harnett A;Geffen D;Ruggeri E.M;Gamucci T;Van Groeningen C.J;Banas R;Alkis N;Hou M.-F;Krie A.K;Vrindavanam N.S;Howard O.M;Citrin D;Morginstin M.S;Desai A;Sanchez I.J;Nixon D.A;Jr;Beatty P.G;Edmiston K;Mclaughlin M;Eneman J.D;Lynch C.A;O'Brien E;Call J.A;Lanier K.S;Conlin A;Brooks D.J;Mcintyre K;Saltzman M.A;Castine M.J;Iii, Ortega G.L;Choi Y.M;Reynolds C.H;Brescia F.A;Kramer R;Kohn A.D;Micha J.P;Rhee J.M;Shah S;Riseberg D.A;Patterson W.K;Salmon J.-P;Andre C;Bols A;D'Hondt R;Luce S;Nouwynck C;Pelgrims G;Richard V;Verschuere J;Geldhof K;Caspar C;Luo R;Bednarik O;Schwedler K;Schmidt M;Neumeister R;Bischoff J;Rack B;Repp R;Fries S;Adrion R;Schulz V;Klare P;Danei M;Ossenbuhl D;Kusche J.M;Griesinger F;Baena Canada J.M;Martinez Del Prado P;Machover D;Mayeur D;Trufflandier N;Delecroix V;Mousseau M;Mouret-Reynier M.-A;Nabholtz J.-M;Chetiyawardana A.D;Papandreou C;Hornyak L;Faluhelyi Z;Simo E;Di Palma M;Cognetti F;Gorzegno G;Dogliotti L;Gridelli C;Falcone A;Soto Parra H;Buscarino C;Im S.-A;Sanchez Llamas B;Dercksen W;Erdkamp F;Ruit J.B;Braun H;Portielje J.E.A;Ciltas A;Buyukberber S;Benekli M;Zahalsky A.J;Jaslow R;Thomas G.W;Maini A;Wiznitzer I;Khojasteh A;Francisco Gonzalez M;Kong L.R;Padmanabhan A;Conkright W.A;Swain S.M;Faig D.E;Jain K;Yanagihara R.H;Ottaviano Y;Delmas A;Steele H.A;Rainey G.K;Harris P.J;Burris J.K;Rupard E.J;Tan E;Whitworth P.W;Bova A.R;Anderson I.C;Shirinian M;Tin-U C;O'Rourke T.J;Roberts M.S;Francisco M;Pierson A.S;Byeff P.D;Kovach P.A;Caton J.R;Jr;Rarick M.U;Schimidt W.G;Jr;Stopeck A.T;Swart R;Carrillo Flores M.R;Alemany C.A;Lozada B;Weinstein P.L;Wang W;Porubcin M;Ellison D.M;Geils G.F;Rivera E;Charif M;Extenet Study Group

Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/494556

Title:	Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial
Authors:	Martin, Miguel Holmes, Frankie A Ejlertsen, Bent Delaloge, Suzette Moy, Beverly Iwata, Hiroji von Minckwitz, Gunter Chia, Stephen K L Mansi, Janine Barrios, Carlos H Gnant, Michael KING-JEN CHANG Arance A.M Efrat N Sarosiek T Grzeda L Manalo Y Smith J.C Vaziri I Healey T Rahim Y Toma?evi? Z Luk C Dingle B Franco S Sorensen P.G Anand A Khan S Fountzilas G Aogi K Shimizu S Mikulova M Denduluri N Spanik S Somer R.A Flynn P.J Coward J Mainwaring P Jerusalem G Segura-Ojezzar C Levy C Delozier T Khayat D ?eparovi? R Coleman R.E Rolles M.J Maisano R Nardi M Ito Y Yumuk P.F Basaran G Serdar Turhal N Wilkinson M.J Green N.B Gokmen E Sidrys A.P Hallmeyer S Testori D.J Sridhar S Chang J Sun Q Jara-Sanchez C Rubio X Garrido M.L De La Haba Rodriguez J.R Bashford A Perello Martorell A Avelia Mestre A Rifa Ferrer J del Barco Berron S Nagy Z Tanaka M Im Y.-H Carroll R.R Dickerson L.C Mace J.R Ruiz Borrego M Rivera R Klein L.M Ruxer R Wilks S.T Kotasek D Popov V Taskova V Marinova-Venkova V Timcheva C Desbiens C Kim S.-B Ayoub J.-P Grenier D Marschner N Tesch H Lueck H.-J Janssen J Schwaner I Wahlstrom S Brix E.H Vallentin S Jakobsen E.H Kristensen D Andreeva A Glavicic V Calvo Plaza I Anton Torres A Veyret C Bergerat J.-P Bourbouloux E Ella W.A Algurafi H Ciceniene A Robinson A Kim S.J Taguchi T Juozaityte E Madretsma S Radema S Czerniawska-Meier M Rogowski W Wagnerova M Richards D.A Inoue K Tan-Chiu E Vasileios A Henderson C.A Holden V.R Wang X Tong Z Yang J Gonzalez M.E Rezai M Hackmann J Overkamp F de Due?as E.M de las Heras B.B Dourthe L.M Chocteau-Bouju D Bougnoux P Kakolyris S Kalofonos H Pectasidis D Ng T.Y Pajkos G Heijns J.B Somogyine E.E Tonini G Giuffrida D Takao S Ishitobi M Inaji H Tokuda Y Wozniak K Lungulescu D YEN-SHEN LU Armstrong A.C Chang K.-J Hill J Croot C.C Dekker A Belman N.D Conde M Michaelson R.A Kemmer K Chui S Luoh S.-W Link J.S Nahum K Greenspan A.R Nichols J.C Encarnacion C.A Niederman T.M.J Lee T Alexander R Gordon R Tomova A Rauch D Joy A.A Popescu R.A Rojas G.A Vanasek J Neunhoeffer T Barinoff J Graffunder G Wolfgang A Bojko P Heinrich B von der Assen A Bryce R Antonovic B.J Adrian L Ramos Vazquez M Gonzalez Santiago S Dieras V Bishop J.M Perren T.J Varthalitis I Mavroudis D Georgoulias V Wong A Chow L.W.C Yau C.C.T Liang R.H.-S Pik? B W?ber A Kaufman B Drumea K Nuzzo F De Matteis A Nuzzo F Moran S Carteni G Tokunaga E Ishida M Ohno S Sato N Kuroi K Nishimura R Watanabe J Choi Y.J Park K.H Yao B Wojtukiewicz M Jassem J Loman N Askoy S Altundag M.K Saip P Ali M.A Wade J.L III, Chien A.J Brandt D Xu F Novik Y Jani C Rice R.L Gaffar Y.A.R Keaton M.R Bajaj R Kimmick G Campbell D De Boer R.H Turnquest T Auerbach A Lucas S Dube P Xu B Schilling J Apel K Sorensen P.G Vestlev P.M Jensen B.B Haahr V Lescure A.R Buyse M Grana Suarez B Saura Manich C Jacquin J.-P Samreen A Boiangiu I Dank M Falci C Jirillo A Cinieri S Ueno T Chan A Sato F Yamashiro H Sugie T Lee K.S Ro J.S Park I.H Bustam A.Z Suszko-Kazarnowicz M Piktel A Krzemieniecki K Harvey V Iorga P.G Yap Y.S Kakalejcik M Sevinc A Ozguroglu M Chen S.-C Greenberg R.H Eisemann A.D Droder R Abbasi M.R Tomek R Vaysburd M Caldera H.J Haley B.B Robin E Inhorn R.C Hufnagel D Kenyon P.D Spremulli E Silverman P Jain S Robert N.J Weigand R Mebis J Koynova T Lesperance B Prausova J Kohne C.-H Schneeweiss A Jackisch C Fuxius S Cubedo Cervera R Gore I Urruticoechea Ribate A Pernas Simon S Valero Gallego J Arcusa Lanza A del Pilar Alvarez M Florian Gerico J Cany L Stebbing J Labudovic D Gugic D Jr Vrbanec D Roila F Barni S Bidoli P Mukai H Bermudez V Eniu A Mirtsching B.C Ibrahim E Trey J Smith J.W Hergenroeder P.F Mahmood A Gonzalez A Kaplan E.H Ban S Patel D Clowney B Hoelzer K Schwartz G.H Salkeni M II, Masuda N Abraham J Narula S Jabboury K Mocharnuk R.S McDonough R.H Sikes D.H Kawanchi R.H Schlabach L McCachren S.S Jr Di Sean Kendall S Cosgriff T.M Dreisbach L DeMichele A Pawl L Lucas J Shinn L.C Alkhouri N Monga M Lindquist D.L Anderson T.C Harker W.G Khurshid H Witherby S Erickson N Traynor A Bose R Pluard T.J Jones M.C Prakash S Volterra F Capo G Petrakova K Flaherty L.E Gartner E Baidas S Okazaki I Nguyen B Rakowski T Oliff I Leach J.W Anderson D Kubiak K Guerrero Zotano A Tsai M Vroman P Deleu I Lybaert W Borms M Couture F Wilson J.J Hunt G Holland D.R Mingrone W Simon A.R Wang S Liu D Jiang Z Benesova V Smakal M Garnolova P Vesper A.-S Neumann M Janni W Liedtke C Konstantinovic Z.N Fischer D Grischke E.-M Seeger D Moebus V Prechtl A Carlos Camara Toral J Sanchez Munoz A Gonzalez Jimenez S Cassinello Espinosa J Cirauqui B Iannotti N.O Margeli Vila M Batista Lopez N Chacon Lopez-Muniz J.I de la Cruz Mora M.A Mailliez A Vanlemmens L Pouessel D Espie M Conibear J Roylance R Tassone P Harnett A Geffen D Ruggeri E.M Gamucci T Van Groeningen C.J Banas R Alkis N Hou M.-F Krie A.K Vrindavanam N.S Rodriguez G.I Howard O.M Citrin D Morginstin M.S Desai A Sanchez I.J Nixon D.A Jr Beatty P.G Edmiston K McLaughlin M J??ez Martinez N Eneman J.D Lynch C.A O'Brien E Call J.A Lanier K.S Conlin A Brooks D.J McIntyre K Saltzman M.A Castine M.J Crespo Massieu C III, Ortega G.L Choi Y.M Reynolds C.H Brescia F.A Kramer R Kohn A.D Micha J.P Rhee J.M Shah S Riseberg D.A Smickoska S Patterson W.K Salmon J.-P Andre C Bols A D'hondt R Luce S Nouwynck C Pelgrims G Richard V Verschuere J Somali I Geldhof K Caspar C Luo R Bednarik O Schwedler K Schmidt M Neumeister R Bischoff J Rack B Repp R Yilmaz U Fries S Adrion R Schulz V Klare P Danei M Ossenbuhl D Kusche J.M Griesinger F Baena Canada J.M Martinez del Prado P Alonso M.G Machover D Mayeur D Trufflandier N Delecroix V Mousseau M Mouret-Reynier M.-A Nabholtz J.-M Chetiyawardana A.D Papandreou C Hornyak L Rosales A.M Faluhelyi Z Simo E Di Palma M Cognetti F Gorzegno G Dogliotti L Gridelli C Falcone A Soto Parra H Buscarino C Cold S Im S.-A Sanchez Llamas B Dercksen W Erdkamp F Ruit J.B Braun H Portielje J.E.A Ciltas A Buyukberber S Benekli M Knoop A.S Zahalsky A.J Jaslow R Thomas G.W Maini A Wiznitzer I Khojasteh A Francisco Gonzalez M Kong L.R Padmanabhan A Conkright W.A Patt D Swain S.M Faig D.E Jain K Yanagihara R.H Ottaviano Y Delmas A Steele H.A Rainey G.K Harris P.J Burris J.K Hellerstedt B.A Rupard E.J Tan E Whitworth P.W Bova A.R Anderson I.C Shirinian M Tin-u C O'Rourke T.J Roberts M.S Francisco M Morales Murillo S Pierson A.S Byeff P.D Kovach P.A Caton J.R Jr Rarick M.U Schimidt W.G Jr Stopeck A.T Swart R Mayer I.A Carrillo Flores M.R Alemany C.A Lozada B Weinstein P.L Wang W Porubcin M Ellison D.M Geils G.F Rivera E Charif M Means-Powell J.A ExteNET Study Group Hui R Senecal F.M De Boer R.H Shen Z Luczak A.A Chui J.W.Y Tsang J.W.-H Lang I Rai Y Hozumi Y Ten Tije A.J Bhandari M Osborne C.R.C Ohtani S Higaki K Watanabe K Taguchi K Takahashi M Filipovic S Hansen V.L Rao V.P Gupta M Petrov P Coudert B Vojnovic Z Polya Z Miyaki T Yamamoto N Brincat S Lesniewski-Kmak K Chmielowska E Birhiray R.E Citron M.L Papish S.W Berry W.R Langkjer S.T
Issue Date:	2017
Publisher:	Lancet Publishing Group
Journal Volume:	18
Journal Issue:	12
Start page/Pages:	1688-1700
Source:	The Lancet Oncology
URI:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85035115011&doi=10.1016%2fS1470-2045%2817%2930717-9&partnerID=40&md5=20933f3981722db96cdf206b58b321e7 https://scholars.lib.ntu.edu.tw/handle/123456789/494556
ISSN:	1470-2045
DOI:	10.1016/S1470-2045(17)30717-9
SDG/Keyword:	[SDGs]SDG3
Appears in Collections:	醫學院附設醫院 (臺大醫院)

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