https://scholars.lib.ntu.edu.tw/handle/123456789/495886
標題: | Prognostic factors for neurologic outcome in patients with carotid artery stenting | 作者: | CHI-SHENG HUNG MAO-SHIN LIN YING-HSIEN CHEN CHING-CHANG HUANG HUNG-YUAN LI HSIEN-LI KAO |
公開日期: | 2016 | 出版社: | Republic of China Society of Cardiology | 卷: | 32 | 期: | 2 | 起(迄)頁: | 205-214 | 來源出版物: | Acta Cardiologica Sinica | 摘要: | Background: Carotid artery stenting (CAS) is a valid treatment for patients with carotid artery stenosis. The long-term outcome and prognostic factors in Asian population after CAS are not clear. This study aimed to identify the prognostic factors among Asian patients who have undergone CAS. Methods: We retrospectively analyzed 246 patients with CAS. Annual carotid duplex ultrasound was used to identify restenosis. Peri-procedural complications, restenosis, neurologic outcomes, and mortality were recorded. Cox regression analyses were used to identify prognostic factors. Results: The mean follow-up time was 49.2 months. Procedural success was achieved in 237 patients (98.3%), and protection devices were used in 208 patients (84.5%). Within 30 days of CAS, 13 (4.3% per procedure) periprocedural complications occurred. During the follow-up period, 24 (9.7%) patients developed restenosis, and 37 (15.0%) developed ischemic strokes. In a multiple logistic regression analysis, head and neck radiotherapy [hazard ratio (HR) = 9.9, 95% confidence interval (CI), 3.38-29.1, p <.001], stent diameter (HR = 0.72, 95% CI, 0.58-0.89, p =.003), and predilatation (HR = 3.08 95% CI, 1.21-7.81, p =.018) were independent predictors for restenosis. In Cox regression analysis, hypercholesterolemia (HR = 0.25, 95% CI, 0.07-0.94, p =.04), head and neck radiotherapy (HR = 6.2, 95% CI, 1.8-21.3, p =.004), and restenosis (HR = 3.6, 95% CI, 1.1-11.18, p =.04) were predictors for recurrent ipsilateral ischemic stroke. Conclusions: CAS provides reliable long-term results in Asian patients with carotid stenosis. Restenosis is associated with an increased rate of recurrent stroke and should be monitored carefully following CAS. ? 2016, Republic of China Society of Cardiology. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84964755814&doi=10.6515%2fACS20150119H&partnerID=40&md5=52c1063ad2b286e77ff6b282ad5b0171 https://scholars.lib.ntu.edu.tw/handle/123456789/495886 |
ISSN: | 1011-6842 | DOI: | 10.6515/ACS20150119H | SDG/關鍵字: | acetylsalicylic acid; clopidogrel; adult; artery diameter; Article; brain hemorrhage; brain ischemia; cardiovascular mortality; carotid artery stenting; cerebrovascular accident; disease free survival; echography; female; head and neck radiation; human; hypercholesterolemia; kidney artery stenosis; major clinical study; male; neurologic outcome; outcome assessment; peroperative complication; prognostic assessment; radiation; restenosis; systolic blood pressure |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。