https://scholars.lib.ntu.edu.tw/handle/123456789/496646
標題: | Associations of remission status and lanreotide treatment with quality of life in patients with treated acromegaly | 作者: | Hua S.-C. Yan Y.-H. TIEN-CHUN CHANG |
公開日期: | 2006 | 卷: | 155 | 期: | 6 | 起(迄)頁: | 831-837 | 來源出版物: | European Journal of Endocrinology | 摘要: | Objective: Acromegaly has an important impact on quality of life (QOL). The aim of this study was to evaluate the associations of remission status and lanreotide treatment with QOL in patients with treated acromegaly, by the newly developed disease-generated acromegaly QOL questionnaire (ACROQOL). Design: Cross-sectional study. Methods: Fifty-two patients with treated acromegaly were recruited to complete the Chinese version of the ACROQOL translated and validated from the English version. These patients were divided into controlled and uncontrolled groups based on the latest remission criteria and further subdivided into four groups according to the present treatment with lanreotide or not. Comparisons between groups were analyzed. Results: There was no difference between controlled and uncontrolled groups in the ACROQOL scores of total score, both scales and psychological subscales. However, in the controlled group, present treatment with lanreotide, in comparison with no treatment, showed worse ACROQOL scores in total score (P=0.021), psychological scale (P=0.011), psychological subscale 'appearance' (P=0.032) and 'personal relations' (P=0.010). Conclusions: The lanreotide treatment was negatively associated with QOL in biochemically controlled acromegalic patients, especially in the psychological aspect. ? 2006 Society of the European Journal of Endocrinology. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33845980194&doi=10.1530%2feje.1.02292&partnerID=40&md5=a0c24093d01528d315abbc26e737979b https://scholars.lib.ntu.edu.tw/handle/123456789/496646 |
ISSN: | 0804-4643 | DOI: | 10.1530/eje.1.02292 | SDG/關鍵字: | angiopeptin; glucocorticoid; sex hormone; thyroxine; acromegaly; adrenal insufficiency; adult; aged; article; Chinese; controlled study; female; hormone substitution; human; hypophysis adenoma; hypopituitarism; hypothyroidism; language; major clinical study; male; microadenoma; priority journal; psychological rating scale; quality of life; questionnaire; remission; scoring system; Acromegaly; Adult; Aged; Antineoplastic Agents; Cohort Studies; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Peptides, Cyclic; Prospective Studies; Quality of Life; Questionnaires; Remission Induction; Somatostatin |
顯示於: | 醫學系 |
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