|Title:||Thyroid disorders in Chinese patients with systemic lupus erythematosus||Authors:||Tsai R.-T.
|Issue Date:||1993||Publisher:||Springer-Verlag||Journal Volume:||13||Journal Issue:||1||Start page/Pages:||9-13||Source:||Rheumatology International||Abstract:||
To clarify the prevalence of thyroid disorders in Chinese patients with systemic lupus erythematosus (SLE), 45 SLE patients not receiving corticosteroid therapy for at least 6 months were selected over a period of 1 year. They were investigated by utilizing thyroid ultrasonography and by determinations of thyroid antibodies and thyroid function. Of these patients, 24 (53.3%) showed abnormal sonographic findings. Thyroid antibodies (microsomal and/or thyroglobulin) were detected in 21 patients (46.7%), but a low index of thyrotropinbinding inhibitory immunoglobulin (TBII) was found in only one euthyroid patient with a normal echogram. Ten patients (22.2%) had abnormal thyroid function. The mean disease duration was longer in patients with thyroid anomalies (p<0.05). Hashimoto's thyroiditis was found in four patients (8.8%), two of whom had hypothyroidism. We concluded that thyroid anomalies are frequently found in patients with SLE in the area of this study. The possibility of the coexistence of thyroid disorders in systemic lupus erythematosus should be carefully considered throught the course of patients' follow-up, especially in those with a long disease duration. ? 1993 Springer-Verlag.
|ISSN:||0172-8172||DOI:||10.1007/BF00290328||SDG/Keyword:||thyroid antibody; thyrotropin receptor; thyrotropin receptor antibody; adult; antibody titer; article; china; clinical article; disease association; echography; female; hashimoto disease; human; male; prevalence; prospective study; systemic lupus erythematosus; thyroid disease; thyroid function; Adult; Antibodies; Human; Lupus Erythematosus, Systemic; Middle Age; Prospective Studies; Receptors, Thyrotropin; Thyroid Diseases
|Appears in Collections:||醫學系|
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