https://scholars.lib.ntu.edu.tw/handle/123456789/506297
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Hsieh C.-H. | en_US |
dc.contributor.author | Shueng P.-W. | en_US |
dc.contributor.author | LI-YING WANG | en_US |
dc.contributor.author | Huang Y.-C. | en_US |
dc.contributor.author | Liao L.-J. | en_US |
dc.contributor.author | Lo W.-C. | en_US |
dc.contributor.author | Lin Y.-C. | en_US |
dc.contributor.author | Wu L.-J. | en_US |
dc.contributor.author | Tien H.-J. | en_US |
dc.date.accessioned | 2020-06-29T02:20:08Z | - |
dc.date.available | 2020-06-29T02:20:08Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1471-2407 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960867350&doi=10.1186%2fs12885-016-2165-9&partnerID=40&md5=76882384b6196e83bf574f30403e51ff | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/506297 | - |
dc.description.abstract | Background: We compared the outcome of patients who received non-image-guided intensity-modulated radiotherapy (IMRT) with those who received helical tomotherapy (HT), a daily image-guided radiotherapy (IGRT), after surgery for oral cavity cancer (OCC). Methods: During the period November 2006 to December 2013, a total of 152 postoperative OCC patients underwent either IMRT (n = 79) or daily IGRT (n = 73) 4 to 6 weeks after surgery. Patients in the IMRT group received 6 MV photon beams to 7 fields and those in the IGRT group received daily fractions of 1.8 or 2 Gy on five consecutive days. Results: Patients who received daily IGRT had higher 5-year overall survival than those who received IMRT (87 % versus 48 %, p = 0.015). The local progression-free survival rate was also higher in patients who received IGRT (85 % versus 58 %, p = 0.006). More patients in the IGRT group completed the package of overall treatment time in ? 13 weeks and completed their course of radiation therapy in ? 8 weeks than patients in the IMRT group (89 % versus 68 %, p = 0.002; 84 % versus 58 %, p = 0.001), respectively. The rate of local failure in the primary tumor area was 24.0 % in the IMRT group and 6.8 % in the IGRT group. Among patients with primary local failure, the marginal failure rate was 52.6 % in the IMRT group and 0 % in the IGRT group. Conclusions: For patients with locally advanced OCC, postoperative IGRT results in better overall survival, better local progression-free survival, less marginal failure and shorter overall treatment time than postoperative non-image-guided IMRT. ? 2016 Hsieh et al. | - |
dc.publisher | BioMed Central Ltd. | - |
dc.relation.ispartof | BMC Cancer | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; advanced cancer; aged; anemia; Article; cancer prognosis; controlled study; dermatitis; disease free survival; dysphagia; female; fistula; human; image guided radiotherapy; intensity modulated radiation therapy; leukopenia; major clinical study; male; metastasis free survival; mouth cancer; mucosa inflammation; overall survival; postoperative care; progression free survival; thrombocytopenia; tomotherapy; treatment failure; weight reduction; xerostomia; comparative study; image guided radiotherapy; intensity modulated radiation therapy; middle aged; Mouth Neoplasms; postoperative period; procedures; radiation dose fractionation; retrospective study; treatment outcome; Adult; Aged; Disease-Free Survival; Dose Fractionation; Female; Humans; Male; Middle Aged; Mouth Neoplasms; Postoperative Period; Radiotherapy, Image-Guided; Radiotherapy, Intensity-Modulated; Retrospective Studies; Treatment Outcome | - |
dc.title | Impact of postoperative daily image-guided intensity-modulated radiotherapy on overall and local progression-free survival in patients with oral cavity cancer | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1186/s12885-016-2165-9 | - |
dc.identifier.pmid | 26906330 | - |
dc.identifier.scopus | 2-s2.0-84960867350 | - |
dc.relation.pages | 139 | - |
dc.relation.journalvolume | 16 | - |
dc.relation.journalissue | 1 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Physical Therapy | - |
crisitem.author.orcid | 0000-0003-3075-6872 | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 物理治療學系所 |
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