https://scholars.lib.ntu.edu.tw/handle/123456789/506308
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Hsieh C.-H. | en_US |
dc.contributor.author | Shueng P.-W. | en_US |
dc.contributor.author | Hsiao S.-M. | en_US |
dc.contributor.author | Wei M.-C. | en_US |
dc.contributor.author | Wu W.-Y. | en_US |
dc.contributor.author | Sun H.-D. | en_US |
dc.contributor.author | Tien H.-J. | en_US |
dc.contributor.author | LI-YING WANG | en_US |
dc.contributor.author | Hsieh Y.-P. | en_US |
dc.creator | Hsieh C.-H.;Shueng P.-W.;Hsiao S.-M.;Wei M.-C.;Wu W.-Y.;Sun H.-D.;Tien H.-J.;Li-Ying Wang;Hsieh Y.-P. | - |
dc.date.accessioned | 2020-06-29T02:20:11Z | - |
dc.date.available | 2020-06-29T02:20:11Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1178-6930 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84873886301&doi=10.2147%2fOTT.S35958&partnerID=40&md5=ae28bdd319417f30155d9457477d7705 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/506308 | - |
dc.description.abstract | Background: The purpose of this study was to compare the efficacy of intensity-modulated radiotherapy (IMRT) and helical tomotherapy for endometrial cancer. Methods: Between November 1, 2006 and November 31, 2010, 31 patients with histologically confirmed endometrial cancer were enrolled. All enrolled patients received total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant whole pelvic IMRT or helical tomotherapy. Results: The actuarial 3-year overall survival, disease-free survival, locoregional control, and distant metastasis-free rates for the IMRT and helical tomotherapy groups were 87.5% versus 100%, 91.7% versus 51.7%, 91.7% versus 83.3%, and 91.7% versus 51.7%, respectively. The conformal index and uniformity index for IMRT versus helical tomotherapy was 1.25 versus 1.17 (P = 0.04) and 1.08 versus 1.05 (P<0.01), respectively. Two of 31 patients with cervical stump failure were noted, one in the IMRT group and the other in the helical tomotherapy group. No acute or late grade 3 or 4 toxicities were noted, including proctitis, or genitourinary or gastrointestinal disturbances. Conclusion: Helical tomotherapy is as effective as IMRT and has better uniformity and conformal indices, and critical organ-sparing properties. Prospective clinical trials are needed to evaluate the comparative efficacy of IMRT versus helical tomotherapy. ? 2012 Hsieh et al, publisher and licensee Dove Medical Press Ltd. | - |
dc.relation.ispartof | OncoTargets and Therapy | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | abdominal hysterectomy; adult; aged; article; brachytherapy; cancer adjuvant therapy; cancer radiotherapy; cancer recurrence; cancer survival; clinical article; comparative effectiveness; controlled study; diarrhea; disease free survival; distant metastasis free survival; dosimetry; endometrium carcinoma; female; human; intensity modulated radiation therapy; leukopenia; local recurrence free survival; metastasis; overall survival; pain; radiation injury; radiotherapy equipment; retrospective study; salpingooophorectomy; tomotherapy; treatment outcome | - |
dc.title | Helical tomotherapy provides efficacy similar to that of intensity-modulated radiation therapy with dosimetric benefits for endometrial carcinoma | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.2147/OTT.S35958 | - |
dc.identifier.scopus | 2-s2.0-84873886301 | - |
dc.relation.pages | 245-253 | - |
dc.relation.journalvolume | 5 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Physical Therapy | - |
crisitem.author.orcid | 0000-0003-3075-6872 | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 物理治療學系所 |
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