https://scholars.lib.ntu.edu.tw/handle/123456789/506313
標題: | Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer | 作者: | Hsieh C.-H. Kuo Y.-S. Liao L.-J. Hu K.-Y. Lin S.-C. Wu L.-J. Lin Y.-C. Chen Y. LI-YING WANG Hsieh Y.-P. Lin S.L. Chen C.-Y. Chen C.-A. Shueng P.-W. |
公開日期: | 2011 | 卷: | 11 | 起(迄)頁: | 37 | 來源出版物: | BMC Cancer | 摘要: | Background: The aim of this study was to assess the treatment results and toxicity profiles of helical tomotherapy (HT) for postoperative high-risk oral cavity cancer.Methods: From December 6, 2006 through October 9, 2009, 19 postoperative high-risk oral cavity cancer patients were enrolled. All of the patients received HT with (84%) or without (16%) chemotherapy.Results: The median follow-up time was 17 months. The 2-year overall survival, disease-free survival, locoregional control, and distant metastasis-free rates were 94%, 84%, 92%, and 94%, respectively. The package of overall treatment time > 13 wk, the interval between surgery and radiation ? 6 wk, and the overall treatment time of radiation ? 7 wk was 21%, 84%, and 79%, respectively. The percentage of grade 3 mucositis, dermatitis, and leucopenia was 42%, 5% and 5%, respectively.Conclusions: HT achieved encouraging clinical outcomes for postoperative high-risk oral cavity cancer patients with high compliance. A long-term follow-up study is needed to confirm these preliminary findings. ? 2011 Hsieh et al; licensee BioMed Central Ltd. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-79251567669&doi=10.1186%2f1471-2407-11-37&partnerID=40&md5=bebca07cce8b77a18ca8a8ffe1e0ece6 https://scholars.lib.ntu.edu.tw/handle/123456789/506313 |
ISSN: | 1471-2407 | DOI: | 10.1186/1471-2407-11-37 | SDG/關鍵字: | cisplatin; fluorouracil; folinic acid; antineoplastic agent; adult; aged; anemia; article; cancer control; cancer survival; chemoradiotherapy; clinical article; controlled study; dermatitis; disease free survival; distant metastasis; female; human; intensity modulated radiation therapy; leukopenia; male; mouth cancer; mucosa inflammation; oral surgery; overall survival; patient compliance; postoperative care; retrospective study; thrombocytopenia; tomotherapy; treatment outcome; weight reduction; xerostomia; clinical trial; drug effect; intensity modulated radiation therapy; leukopenia; methodology; middle aged; mouth; mouth tumor; mucosa inflammation; multimodality cancer therapy; postoperative care; radiation dermatitis; radiation dose; radiation exposure; risk factor; spiral computer assisted tomography; Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Leukopenia; Male; Middle Aged; Mouth; Mouth Neoplasms; Mucositis; Postoperative Care; Radiodermatitis; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Risk Factors; Tomography, Spiral Computed; Treatment Outcome; Young Adult |
顯示於: | 物理治療學系所 |
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