https://scholars.lib.ntu.edu.tw/handle/123456789/507776
標題: | DBCAT: Database of CpG islands and analytical tools for identifying comprehensive methylation profiles in cancer cells | 作者: | Kuo, H.-C. Lin, P.-Y. Chung, T.-C. Chao, C.-M. LIANG-CHUAN LAI Tsai, M.-H. MONG-HSUN TSAI ERIC YAO-YU CHUANG |
公開日期: | 2011 | 卷: | 18 | 期: | 8 | 起(迄)頁: | 1013-1017 | 來源出版物: | Journal of Computational Biology | 摘要: | DBCAT (database of CpG islands and analytical tools, http://dbcat.cgm.ntu. edu.tw/), developed to characterize comprehensive DNA methylation profiles in human cancers, is a web-based application and methylation database containing several convenient tools for investigating epigenetic regulation in human diseases. To our knowledge, DBCAT is the first online methylation analytical tool, and is composed of three parts: a CpG island finder, a genome query browser, and a tool for analyzing methylation microarray data. The analytical tools can quickly identify genes with methylated regions from microarray data, compare the methylation status changes between different arrays, and provide functional analysis in addition to colocalizing transcription factor binding sites. ? Copyright 2011, Mary Ann Liebert, Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-79961145731&doi=10.1089%2fcmb.2010.0038&partnerID=40&md5=984ff972079166d4d27953e663401c39 https://scholars.lib.ntu.edu.tw/handle/123456789/507776 |
ISSN: | 1066-5277 | DOI: | 10.1089/cmb.2010.0038 | SDG/關鍵字: | transcription factor; article; binding site; computer program; CpG island; DNA methylation; epigenetics; gene expression profiling; gene expression regulation; genetic database; genetics; human; human genome; metabolism; methodology; neoplasm; promoter region; protein binding; Binding Sites; CpG Islands; Databases, Genetic; DNA Methylation; Epigenomics; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome, Human; Humans; Neoplasms; Promoter Regions, Genetic; Protein Binding; Software; Transcription Factors |
顯示於: | 生理學科所 |
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