https://scholars.lib.ntu.edu.tw/handle/123456789/509432
Title: | Vascular and hepatic enhancements at MR imaging: Comparison of Gd-EOB-DTPA and Gd-DTPA in the same subjects | Authors: | YEN-HENG LIN Hwang R.-M. BANG-BIN CHEN CHAO-YU HSU CHIH-WEI YU JIA-HORNG KAO Lee, Hsuan-Shu PO-CHIN LIANG Wei S.-Y. TIFFANY TING-FANG SHIH |
Issue Date: | 2014 | Journal Volume: | 38 | Journal Issue: | 3 | Start page/Pages: | 287-291 | Source: | Clinical Imaging | Abstract: | Objective: The objective was to compare vascular and hepatic enhancement differences at magnetic resonance imaging (MRI) between Gd-EOB-DTPA and Gd-DTPA in the same subjects. Methods: Ten healthy subjects received dynamic contrast-enhanced MRI (DCE-MRI) with Gd-EOB-DTPA and then Gd-DTPA to obtain quantitative parameters at 60 and 100 s, respectively. Results: At 60 s, no difference was noted in DCE-MRI parameters between the two contrast agents. At 100 s, mean transit time (MTT) was higher in Gd-EOB-DTPA than in Gd-DTPA (P=008). Conclusions: Gd-EOB-DTPA showed vascular and hepatic enhancement similar to Gd-DTPA within the initial 60 s during the dynamic phase, but showed increased MTT due to hepatocytes uptake at 100 s. ? 2014 Elsevier Inc. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/509432 | ISSN: | 0899-7071 | DOI: | 10.1016/j.clinimag.2014.01.001 | SDG/Keyword: | Medical imaging; Radiology; DCE-MRI; Dynamic contrast enhanced MRI; Gd-DTPA; Gd-EOB-DTPA; Healthy subjects; Mean transit time; Perfusion imaging; Quantitative parameters; Magnetic resonance imaging; gadolinium pentetate; gadoxetic acid; contrast medium; gadolinium pentetate; gadoxetic acid; adult; article; contrast enhancement; controlled study; female; hepatobiliary radiography; hepatography; human; human experiment; image analysis; intermethod comparison; male; middle aged; normal human; nuclear magnetic resonance imaging; priority journal; quantitative analysis; reaction time; recommended drug dose; signal noise ratio; tissue distribution; clinical trial; comparative study; cytology; diagnostic use; hepatic artery; image enhancement; liver; liver vein; magnetic resonance angiography; nuclear magnetic resonance imaging; portal vein; procedures; vascularization; Adult; Contrast Media; Female; Gadolinium DTPA; Hepatic Artery; Hepatic Veins; Humans; Image Enhancement; Liver; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Middle Aged; Portal Vein |
Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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