https://scholars.lib.ntu.edu.tw/handle/123456789/510302
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Huang J.-W. | en_US |
dc.contributor.author | Pan H.-J. | en_US |
dc.contributor.author | Yao W.-Y. | en_US |
dc.contributor.author | Tsao Y.-W. | en_US |
dc.contributor.author | WEI-YU LIAO | en_US |
dc.contributor.author | Wu C.-W. | en_US |
dc.contributor.author | Tung Y.-C. | en_US |
dc.contributor.author | Lee C.-H. | en_US |
dc.creator | Huang J.-W.;Pan H.-J.;Yao W.-Y.;Tsao Y.-W.;Wei-Yu Liao;Wu C.-W.;Tung Y.-C.;Lee C.-H. | - |
dc.date.accessioned | 2020-07-21T06:09:15Z | - |
dc.date.available | 2020-07-21T06:09:15Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1473-0197 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84875826879&doi=10.1039%2fc2lc41050h&partnerID=40&md5=7bb44fae7a6a50360d2b9cd2c2351008 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/510302 | - |
dc.description.abstract | Using a cell culture chip with a deformable substrate driven by a hydraulic force, we investigated the motility of cancer cells affected by myofibroblasts undergoing cyclic tensile strain (CTS). CTS reduced both the expression of α-smooth muscle actin in the myofibroblast and the ability of the myofibroblast to accelerate cancer cell migration. However, with the treatment of a pro-inflammatory factor interleukin-1β on the myofibroblasts, the effects of CTS on the myofibroblast were diminished. This result suggests an antagonism between mechanical and chemical stimulations on mediating cancer metastasis by the stromal myofibroblast. ? 2013 The Royal Society of Chemistry. | - |
dc.publisher | Royal Society of Chemistry | - |
dc.relation.ispartof | Lab on a Chip | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | alpha smooth muscle actin; interleukin 1beta; article; cancer cell; cancer cell culture; cell interaction; cell migration; cell motility; controlled study; cyclic tensile strain; force; human; human cell; hydraulic conductivity; lung cancer; mechanical stimulation; metastasis; myofibroblast; priority journal; protein expression; stimulation; stroma cell; tensile strength | - |
dc.title | Interaction between lung cancer cell and myofibroblast influenced by cyclic tensile strain | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1039/c2lc41050h | - |
dc.identifier.scopus | 2-s2.0-84875826879 | - |
dc.relation.pages | 1114-1120 | - |
dc.relation.journalvolume | 13 | - |
dc.relation.journalissue | 6 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-6383-3470 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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