https://scholars.lib.ntu.edu.tw/handle/123456789/510438
標題: | Factors influencing visibility and diagnostic yield of transbronchial biopsy using endobronchial ultrasound in peripheral pulmonary lesions | 作者: | CHUN-TA HUANG CHAO-CHI HO Tsai Y.-J. CHONG-JEN YU PAN-CHYR YANG |
公開日期: | 2009 | 卷: | 14 | 期: | 6 | 起(迄)頁: | 859-864 | 來源出版物: | Respirology | 摘要: | Background and objective: Endobronchial ultrasound (EBUS) has increased the diagnostic yield of bronchoscopic biopsy of peripheral pulmonary lesions (PPL). However, certain lesions cannot be localized by EBUS, and the factors associated with the visibility of PPL by EBUS have not been investigated. This study evaluated the factors predicting the visualization of EBUS in PPL and the diagnostic yield of EBUS-guided transbronchial biopsy (TBB). Methods: n 2007, 83 patients with PPL underwent EBUS-guided TBB, and their medical records were reviewed and analysed retrospectively. Results: Of the 83 patients examined, EBUS images could not be obtained in 23 patients (28%). Lesion size was a determining factor for the visibility of PPL, with the visualization yield of EBUS in lesions <20 mm being significantly lower than that in lesions ?20 mm (P < 0.001). A definitive diagnosis of PPL localized by EBUS was established using EBUS-guided TBB in 73% of patients. There were no significant differences in diagnostic yield related to underlying disease, lobar distribution, CT scan appearance or presence of complications. Multivariate analysis revealed that the location of PPL on CT scans and position of the probe were independent predictors of the diagnostic yield by EBUS-guided TBB (P < 0.001 and P = 0.001, respectively). Conclusions: Lesion size is a significant factor predicting visualization of EBUS for PPL. The location of PPL on CT scans and position of the probe are significantly related to a higher diagnostic yield with EBUS-guided TBB. ? 2009 The Authors. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-69049120316&doi=10.1111%2fj.1440-1843.2009.01585.x&partnerID=40&md5=18241d9d602eab3a644aa32f961c464c https://scholars.lib.ntu.edu.tw/handle/123456789/510438 |
ISSN: | 1323-7799 | DOI: | 10.1111/j.1440-1843.2009.01585.x | SDG/關鍵字: | adult; aged; article; bronchus biopsy; clinical evaluation; computer assisted tomography; diagnostic accuracy; diagnostic imaging; diagnostic procedure; diagnostic value; endobrochial ultrasound; female; human; lung lesion; major clinical study; male; medical record review; multivariate analysis; prediction and forecasting; priority journal; retrospective study; screening; ultrasound; visibility; Adult; Aged; Aged, 80 and over; Biopsy; Bronchoscopy; Endosonography; Female; Humans; Lung; Lung Diseases; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Radiography, Thoracic; Retrospective Studies; Tomography, X-Ray Computed; Young Adult |
顯示於: | 醫學系 |
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