https://scholars.lib.ntu.edu.tw/handle/123456789/510998
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wu C.-F. | en_US |
dc.contributor.author | YEE-FAN LEE | en_US |
dc.contributor.author | WEN-JENG LEE | en_US |
dc.contributor.author | CHI-TING SU | en_US |
dc.contributor.author | Lee L.J.-H. | en_US |
dc.contributor.author | KWAN-DUN WU | en_US |
dc.contributor.author | PAU-CHUNG CHEN | en_US |
dc.contributor.author | Kao T.-W. | en_US |
dc.creator | Wu C.-F.;Lee Y.-F.;Wen-Jeng Lee;Su C.-T.;Lee L.J.-H.;Wu K.-D.;Chen P.-C.;Kao T.-W. | - |
dc.date.accessioned | 2020-08-05T02:46:13Z | - |
dc.date.available | 2020-08-05T02:46:13Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0929-6646 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/510998 | - |
dc.description.abstract | Background/Purpose Vascular calcification can predict cardiovascular (CV) morbidity and mortality in patients with end-stage renal disease. We evaluated the prevalence, association factors, and outcomes of chest X-ray-detected aortic arch calcification (AoAC) in patients undergoing peritoneal dialysis (PD). Methods We included 190 patients undergoing PD (mean age, 52.6?±?14.3?years) for whom chest radiographs were available. AoAC revealed by chest X-ray was graded from 0 to 3 according to an AoAC score (AoACS). Multiple regression analyses were used to determine the factors associated with AoACS. After adjusting for age, sex, PD duration, diabetes mellitus, mean blood pressure, and history of CV disease, the association between AoAC grading and mortality were assessed using the Kaplan–Meier curve and Cox proportional hazard model. Results Age (p?<?0.001), PD duration (p?=?0.004), history of CV disease (p?<?0.001), and renal Kt/V (p?=?0.031) were associated with AoACS. After a mean follow-up of 55.1?±?32.1?months, patients with Grade 2 (p?=?0.011) or Grade 3 (p?<?0.001) AoAC had higher all-cause mortality than patients with Grade 0 AoAC. In addition, patients with Grades 2 and 3 AoAC had higher CV-related mortality than those with Grades 0 and 1 AoAC (p?=?0.013). Grade 2 [hazard ratio (HR)?=?2.736; 95% confidence interval (CI), 1.038–7.211; p?=?0.042] and Grade 3 AoAC (HR?=?3.289; 95% CI, 1.156–9.359; p?=?0.026) remained associated with all-cause mortality after adjustment. Similarly, Grades 2 and 3 AoAC (HR?=?36.05; 95% CI, 3.494–372; p?=?0.026) significantly correlated with CV mortality after adjustment. Conclusion In patients undergoing PD, CXR-detected severe AoAC was an independent risk factor for all-cause and CV mortalities. ? 2016 | en_US |
dc.relation.ispartof | Journal of the Formosan Medical Association | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | ferritin; high density lipoprotein cholesterol; serum albumin; adult; age; aged; albumin blood level; aortography; artery calcification; Article; cardiovascular disease; cardiovascular mortality; cardiovascular risk; cholesterol blood level; clinical outcome; cohort analysis; diabetes mellitus; diabetic nephropathy; diastolic blood pressure; disease association; disease severity; end stage renal disease; event free survival; female; ferritin blood level; follow up; hemodialysis patient; human; major clinical study; male; mean arterial pressure; medical history; middle aged; morbidity; peritoneal dialysis; prediction; prevalence; prognosis; prospective study; sex; survival rate; systolic blood pressure; thorax radiography; treatment duration; aortic disease; blood vessel calcification; chronic kidney failure; complication; diagnostic imaging; evaluation study; Kaplan Meier method; mortality; pathology; peritoneal dialysis; proportional hazards model; radiography; regression analysis; risk factor; thoracic aorta; time factor; Adult; Aged; Aorta, Thoracic; Aortic Diseases; Cardiovascular Diseases; Female; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Proportional Hazards Models; Radiography; Regression Analysis; Risk Factors; Time Factors; Vascular Calcification | - |
dc.title | Severe aortic arch calcification predicts mortality in patients undergoing peritoneal dialysis | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.jfma.2016.06.006 | - |
dc.identifier.pmid | 27497908 | - |
dc.identifier.scopus | 2-s2.0-84998865641 | - |
dc.relation.pages | 366-372 | en_US |
dc.relation.journalvolume | 116 | en_US |
dc.relation.journalissue | 5 | en_US |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Medical Imaging-NTUH | - |
crisitem.author.dept | Medical Imaging-NTUH | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Medicine-NTUCC | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Institute of Environmental and Occupational Health Sciences | - |
crisitem.author.dept | Environmental and Occupational Medicine-NTUH | - |
crisitem.author.orcid | 0000-0002-7528-3493 | - |
crisitem.author.orcid | 0000-0003-3267-4811 | - |
crisitem.author.orcid | 0000-0002-2926-3950 | - |
crisitem.author.orcid | 0000-0002-3339-1509 | - |
crisitem.author.orcid | 0000-0002-6242-5974 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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