https://scholars.lib.ntu.edu.tw/handle/123456789/511093
標題: | Prognostic indicators for survival after resection of gastric adenocarcinoma | 作者: | WEN-JENG LEE WEN-CHUNG LEE Yeh H.-T. CHIA-TUNG SHUN Wei T.-C. Chen K.-M. |
公開日期: | 1994 | 卷: | 27 | 期: | 4 | 起(迄)頁: | 2483-2490 | 來源出版物: | Journal of Surgical Association Republic of China | 摘要: | From 1978 to 1987, 472 patients with primary gastric adenocarcinoma underwent gastrectomy. Curative resection was possible in 415 patients (87.9%) including 265 (56.1%) absolutely curative and 150 (31.8%) relatively curative resection. Actuarial 5-year survival rate for this series was 35.7% with a 30-day operative mortality of 3.4%. Univariate analysis disclosed: Borrmann type, tumor site, size, node number, tumor invasion depth, esophageal or duodenal invasion, vascular or perineural invasion, section line involvement, gastrectomy type, resection status and combined resection; all had influence on survival. A multivariate survival analysis using Cox model revealed five significant variables predictive of long-term survival following resection of gastric cancer-four were inherent clinicopathologic factors: (1) presence of lymph node metastasis, (2) depth of cancer invasion, (3) esophageal invasion, (4) presence of metastasis, one treatment factor that was possible controlled by the surgeons : (5) status of surgical resection. The five-year survival rate following absolutely curative, relatively curative and non-curative resection were 54.4%, 13.7% and 5.3% respectively. The results suggest that radical gastrectomy and extensive lymphadenectomy provide the best chance of survival for gastric cancer patients. However, only patients without lymph node involvement may well treated by surgery alone, but other patients require multimodal therapy to improve their prognosis. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/511093 | ISSN: | 1011-6788 | SDG/關鍵字: | adenocarcinoma; adult; aged; article; cancer survival; female; gastrectomy; human; lymphadenectomy; major clinical study; male; prognosis; stomach carcinoma |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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