https://scholars.lib.ntu.edu.tw/handle/123456789/511370
標題: | Initial institutional experience of uncooled single-antenna microwave ablation for large hepatocellular carcinoma | 作者: | PO-CHIN LIANG HONG-SHIEE LAI TIFFANY TING-FANG SHIH CHIH-HORNG WU KAI-WEN HUANG |
公開日期: | 2015 | 卷: | 70 | 期: | 5 | 起(迄)頁: | e35-e40 | 來源出版物: | Clinical Radiology | 摘要: | Aim: To evaluate the safety, efficacy, and feasibility of a novel microwave generator, designed to deliver automatically adjusted energy by tissue permittivity feedback control into the tumour via an uncooled antenna, in patients with larger hepatocellular carcinoma (HCC). Materials and methods: Fourteen patients with HCC >5 cm in diameter received surgical or percutaneous microwave ablation with more than 12 months of follow-up. Microwave ablation was performed using a 902-928 MHz generator at 28 W; a single 14 G antenna without water-cooled system was used. The patients were followed up with contrastenhanced CT and serum alpha-foetoprotein to monitor for tumour recurrence at 1 month and then every 3 months after tumour ablation. Results: The follow-up duration for the 11 male and three female patients (mean tumour size 5.77 cm, range 5-7 cm; mean age 63.8 years) was 15.8 months. The mean ablation time was 2025 s (range 900-3600 s), and the mean ablation session was 2.5 (range 1-4). The complete ablation rate was 85% (17 of 20). Local recurrence rate was 5.8% (1 of 17). All patients survived and the morbidity and mortality rate was 21.4% and 0%, respectively. Conclusions: Microwave tissue ablation using this novel system with tissue permittivity feedback control and a single uncooled antenna has a high complete ablation rate and lower morbidity. It proved to be a fast, easy, and effective option for ablation of large (>5 cm) tumours. ? 2015 The Royal College of Radiologists. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/511370 | ISSN: | 0009-9260 | DOI: | 10.1016/j.crad.2015.01.011 | SDG/關鍵字: | alpha fetoprotein; contrast medium; adult; aged; alpha fetoprotein blood level; antenna; Article; cancer mortality; cancer survival; clinical article; computer assisted tomography; contrast enhancement; device safety; female; follow up; generator; human; liver cell carcinoma; liver function; male; microwave generator; microwave radiation; microwave therapy; middle aged; morbidity; priority journal; tumor ablation; tumor recurrence; tumor volume; very elderly; Carcinoma, Hepatocellular; catheter ablation; diagnostic use; Liver Neoplasms; procedures; radiography; therapeutic use; treatment outcome; Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Catheter Ablation; Contrast Media; Female; Humans; Liver Neoplasms; Male; Microwaves; Middle Aged; Tomography, X-Ray Computed; Treatment Outcome |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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