https://scholars.lib.ntu.edu.tw/handle/123456789/511454
標題: | Diabetic ketoacidosis and hypogonadotropic hypogonadism in association with transfusional hemochromatosis in a man with beta-thalassemia major | 作者: | JIN-YING LU CHING-CHUNG CHANG Tsai H.-C. Lin K.-S. Tsang Y.M. Huang K-.M. |
關鍵字: | diabetic ketoacidosis; Hypogonadotropic hypogonadism; Transfusional hemochromatosis | 公開日期: | 2001 | 卷: | 100 | 期: | 7 | 起(迄)頁: | 492-496 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | We report a 23-year-old man with β-thalassemia major and transfusional hemochromatosis, which manifested as diabetic ketoacidosis and hypogonadotropic hypogonadism. This unusual presentation of diabetic ketoacidosis in hemochromatosis has rarely been reported. Magnetic resonance imaging of the abdomen showed decreased signal intensity in the liver, spleen, and pancreas. In addition, the pituitary gland also showed heterogeneous low signal intensity, compatible with hemochromatosis. He was treated with insulin supplements and pulsatile human chorionic gonadotropin administration. Clinical improvement was noted after hormone replacement. Intensive iron chelation therapy was given to prevent cardiac complications, and to restore his gonadal function. During follow-up, the patient experienced improvement in libido and sexual potency. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034821642&partnerID=40&md5=dc67074cdc3939c7acf01041c54ac7e2 https://scholars.lib.ntu.edu.tw/handle/123456789/511454 |
ISSN: | 0929-6646 | SDG/關鍵字: | chorionic gonadotropin; deferoxamine; glucose; gonadorelin; hemoglobin; insulin; iron; testosterone; abdomen; adult; article; beta thalassemia; case report; clinical feature; diabetes mellitus; diabetic ketoacidosis; disease association; drug pulse therapy; erythrocyte transfusion; follow up; gonad function; heart disease; hemochromatosis; hormone substitution; human; hypogonadotropic hypogonadism; hypophysis; iron chelation; libido; liver; male; nuclear magnetic resonance imaging; pancreas; sexual function; signal transduction; spleen; thalassemia major; Adult; beta-Thalassemia; Blood Transfusion; Diabetic Ketoacidosis; Hemochromatosis; Humans; Hypogonadism; Male |
顯示於: | 醫學系 |
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