https://scholars.lib.ntu.edu.tw/handle/123456789/512837| Title: | Development of a PD-L1-Expressing Orthotopic Liver Cancer Model: Implications for Immunotherapy for Hepatocellular Carcinoma | Authors: | DA-LIANG OU Lin, Yu-Yang CHIA-LANG HSU Lin, Yin-Yao Chen, Chia-Wei Yu, Jhang-Sian SHI-CHUEN MIAW PING-NING HSU ANN-LII CHENG CHIUN HSU |
Keywords: | Anti-programmed cell death-1; CD8+ T cells; Immune checkpoint inhibitor; Sorafenib; Tumor-infiltrating lymphocytes;Anti-programmed cell death-1; CD8+ T cells; Immune checkpoint inhibitor; Sorafenib; Tumor-infiltrating lymphocytes | Issue Date: | May-2019 | Publisher: | KARGER | Journal Volume: | 8 | Journal Issue: | 3 | Start page/Pages: | 155 | Source: | Liver cancer | Abstract: | Anti-programmed cell death-1(anti-PD1) treatment has shown promising antitumor efficacy in patients with advanced hepatocellular carcinoma (HCC). This study sought to explore the functional significance of programmed death ligand-1 (PD-L1) expression in tumor cells in the tumor microenvironment. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/512837 | ISSN: | 2235-1795 | DOI: | 10.1159/000489318 | SDG/Keyword: | antineoplastic agent; programmed death 1 ligand 1; rmp 114; sorafenib; unclassified drug; animal cell; animal experiment; animal model; Article; cancer immunotherapy; cancer transplantation; cell growth; cell proliferation; colony formation; controlled study; echography; flow cytometry; human; human cell; in vitro study; liver cancer cell line; liver cell carcinoma; liver transplantation; lymphocyte function; mouse; nonhuman; priority journal; protein expression; tumor microenvironment [SDGs]SDG3 |
| Appears in Collections: | 免疫學研究所 |
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