https://scholars.lib.ntu.edu.tw/handle/123456789/513381
Title: | N-butyl cyanoacrylate embolization as the primary treatment of acute hemodynamically unstable lower gastrointestinal hemorrhage | Authors: | Huang C.-C. CHUNG-WEI LEE Hsiao J.-K. Leung P.-C. KAO-LANG LIU Tsang Y.-M. HON-MAN LIU |
Issue Date: | 2011 | Journal Volume: | 22 | Journal Issue: | 11 | Start page/Pages: | 1594-1599 | Source: | Journal of Vascular and Interventional Radiology | Abstract: | Purpose: To evaluate N-butyl cyanoacrylate (NBCA) embolization as the primary treatment for patients with severe and acute hemodynamically unstable lower gastrointestinal bleeding. Materials and Methods: Twenty-seven patients with acute, unstable hemodynamics caused by lower gastrointestinal bleeding underwent therapeutic NBCA microcatheter embolization over a period of 27 months. The inclusion criteria were hematochezia or melena and hypotension refractory to conservative treatment and requiring blood transfusion. Bleeding was localized to the rectum, colon, or small intestine in all nine such cases. Fifteen patients had severe underlying comorbidities, including sepsis, respiratory failure, malignancy, or renal failure. Results: The procedure was technically successful in all patients. Twenty-six patients were treated solely with NBCA, and one required microcoil embolization. Embolization was performed at the level of the arteria recta or as close as possible to the point of bleeding. Immediate hemostasis occurred in all cases. Four patients experienced repeat hemorrhage, one of whom died. The other three were treated successfully with repeat NBCA embolization. None of the surviving patients had evidence of bowel ischemia. In addition, none of the patients with severe underlying disease died during the follow-up period (range, 3 mo to 2 y). Conclusions: The present findings suggest that NBCA embolization may be a safe alternative treatment for the management of lower gastrointestinal bleeding. Further studies are warranted to confirm the findings. ? 2011 SIR. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/513381 | ISSN: | 1051-0443 | DOI: | 10.1016/j.jvir.2011.07.018 | SDG/Keyword: | enbucrilate; adolescent; adult; aged; article; artificial embolism; blood transfusion; clinical article; coil embolization; colon hemorrhage; comorbidity; conservative treatment; female; follow up; gastrointestinal hemorrhage; hematochezia; hemodynamics; hemostasis; human; hypotension; kidney failure; male; melena; priority journal; rectum hemorrhage; respiratory failure; sepsis; small intestine hemorrhage; treatment outcome; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Catheters; Embolization, Therapeutic; Enbucrilate; Equipment Design; Female; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Male; Middle Aged; Miniaturization; Radiography, Interventional; Recurrence; Retrospective Studies; Severity of Illness Index; Taiwan; Time Factors; Treatment Outcome |
Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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