https://scholars.lib.ntu.edu.tw/handle/123456789/513420
Title: | MRI-guided needle localization for breast lesions occult in mammograms and ultrasound | Authors: | Wang Y.-T. CHIUN-SHENG HUANG Lee H.-T. YEUN-CHUNG CHANG HON-MAN LIU |
Issue Date: | 2008 | Journal Volume: | 33 | Journal Issue: | 1 | Start page/Pages: | 1-7 | Source: | Chinese Journal of Radiology | Abstract: | To evaluate the diagnostic efficacy of breast magnetic resonance imaging (MRI)-guided needle localization and surgical biopsy for suspicious breast lesions occult on physical breast examination, mammography and second-look ultrasound. Twelve patients (age range, 29-68 years; mean 44.9±9.24 years) received breast MR-guided needle localization and surgical biopsy for the suspicious lesions detected by breast MRI only. All procedures were successfully performed in a 1.5T MR system equipped with dedicated breast biopsy system. Eleven of the patients received lateral approach and one received medial approach with a 20-gauge MR-compatible localization needle. Contrast enhancement was given before or after deployment of the hookwire to confirm the location of the hookwire and the suspicious breast lesion. The size of breast lesions ranged from 0.6 to 5 cm (mean±SD, 1.44±1.29cm). Final pathologic diagnoses from surgical specimens included two low grade ductal carcinoma in situ (16.7%). There were three lesions (25%) diagnosed as pre-malignant or high risk lesions, including 1 lobular carcinoma in situ (LCIS) and atypical ductal hyperplasia (ADH), 1 atypical lobular hyperplasia (ALH) and papilloma, and 1 ADH. Seven lesions (58.3%) were benign fibrocystic change (n=5), fibroadenomatous change (n=1) and an intraductal papilloma (n=1). There was no procedure-related complication. No definite abnormality was found in specimen mammograms in seven patients. MRI-guided needle localization of breast lesions provides a confident approach for suspicious lesions detected only on MRI which cannot be biopsied under ultrasound or mammography guidance. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/513420 | ISSN: | 1018-8940 | SDG/Keyword: | adult; aged; article; benign tumor; breast biopsy; breast carcinoma; breast examination; breast fibroadenoma; breast hyperplasia; breast papilloma; breast tumor; cancer diagnosis; contrast enhancement; controlled study; diagnostic accuracy; diagnostic value; echomammography; female; human; imaging system; intraductal carcinoma; major clinical study; mammography; needle biopsy; nuclear magnetic resonance imaging; precancer |
Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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