https://scholars.lib.ntu.edu.tw/handle/123456789/514244
Title: | Less-invasive MR indices of clinically evident esophageal variceal bleeding in biliary atresia patients | Authors: | Mo Y.H. HUEY-LING CHEN WEN-MING HSU STEVEN SHINN-FORNG PENG |
Issue Date: | 2012 | Journal Volume: | 111 | Journal Issue: | 9 | Start page/Pages: | 482-488 | Source: | Journal of the Formosan Medical Association | Abstract: | Background/Purpose: Esophageal variceal hemorrhaging is potentially life threatening for long-term survivors of biliary atresia. We evaluated the feasibility of less-invasive parameters for predicting the presence of clinically significant esophageal variceal bleeding in biliary atresia patients. Methods: A total of 30 patients aged 108-5314 days (median = 285 days) with biliary atresia underwent a magnetic resonance examination with fast spin-echo T2-weighted imaging and spin-echo, T1-weighted images with fat saturation after use of a contrast medium on a 1.5-tesla scanner. The splenic length-platelet ratio was divided by the each patient's body height (m) to produce the corrected splenic length-platelet ratios. In addition, the splenic volume index-to-platelet count ratio was divided by the patient's body weight (kg) to produce a corrected ratio. Results: The corrected splenic length-platelet ratio was more significantly increased in 21 patients with esophageal variceal bleeding (Group A) than in nine patients without variceal bleeding [(Group B) 0.98 ± 0.64 vs. 0.44 ± 0.18, p < 0.01]. The splenic volume index-to-platelet count ratio corrected by body weight was significantly larger in Group A (510.7 ± 536.2) than in Group B (148.1±88.9, p < 0.01). Conclusion: Less-invasive indices, including the corrected splenic length platelet ratio and the splenic volume index-to-platelet count ratio, may be valuable predictors of esophageal variceal bleeding in patients with biliary atresia. ? 2012. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/514244 | ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2011.06.024 | SDG/Keyword: | albumin; bilirubin; contrast medium; adult; aged; albumin blood level; analytical parameters; article; bile duct atresia; bilirubin blood level; body height; body weight; clinical article; controlled study; esophagus surgery; esophagus varices bleeding; female; human; ligation; male; non invasive procedure; nuclear magnetic resonance imaging; organ size; prothrombin time; spleen; splenic length platelet ratio; splenic volume index to platelet count ratio; thrombocyte; thrombocyte count; Adolescent; Biliary Atresia; Child; Child, Preschool; Contrast Media; End Stage Liver Disease; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Infant; Magnetic Resonance Imaging; Male; Platelet Count; Retrospective Studies; Spleen; Survivors |
Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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