https://scholars.lib.ntu.edu.tw/handle/123456789/514334
標題: | Left ventricular regional myocardial motion and twist function in repaired tetralogy of Fallot evaluated by magnetic resonance tissue phase mapping | 作者: | Chang M.-C. Wu M.-T. Weng K.-P. MAO-YUAN SU Menza M. Huang H.-C. Peng H.-H. |
公開日期: | 2018 | 卷: | 28 | 期: | 1 | 起(迄)頁: | 104-114 | 來源出版物: | European Radiology | 摘要: | Objectives: We aimed to characterise regional myocardial motion and twist function in the left ventricles (LV) in patients with repaired tetralogy of Fallot (rTOF) and preserved LV global function. Methods: We recruited 47 rTOF patients and 38 age-matched normal volunteers. Tissue phase mapping (TPM) was performed for evaluating the LV myocardial velocity in longitudinal, radial, and circumferential (Vz, Vr, and V?) directions in basal, middle, and apical slices. The V? peak-to-peak (PTP) during systolic phases, the rotation angle of each slice, and V? inconsistency were computed for evaluating LV twist function and V? dyssynchrony. Results: As compared to the controls, the rTOF patients presented decreased RV ejection fraction (RVEF) (p = 0.002) and preserved global LV ejection fraction (LVEF). They also demonstrated decreased systolic and diastolic Vz in several LV segments and higher diastolic Vr in the septum (all p < 0.05). A lower V? PTP, higher V? inconsistency, and reduced peak net rotation angle (all p < 0.05) were observed. The aforementioned indices demonstrated an altered LV twist function in rTOF patients in an early disease stage. Conclusions: MR TPM could provide information about early abnormalities of LV regional motion and twist function in rTOF patients with preserved LV global function. Key points: ? Patients with rTOF presented significantly reduced systolic and diastolic Vz in the LV. ? rTOF patients demonstrated significantly increased diastolic Vr in the septum. ? Abnormal characteristics of the segmental dynamic velocity evolution were shown in rTOF. ? rTOF patients presented altered circumferential rotation and velocity inconsistency in early stage. ? 2017, European Society of Radiology. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/514334 | ISSN: | 0938-7994 | DOI: | 10.1007/s00330-017-4908-7 | SDG/關鍵字: | adult; Article; cardiac imaging; controlled study; diastole; Fallot tetralogy; female; heart left ventricle ejection fraction; heart left ventricle failure; heart left ventricle function; heart movement; heart preservation; heart right ventricle ejection fraction; human; left ventricle twist function; left ventricular regional myocardial motion; major clinical study; male; nuclear magnetic resonance imaging; priority journal; radiation measurement; systole; three dimensional imaging; tissue phase mapping; young adult; diagnostic imaging; Fallot tetralogy; heart left ventricle function; heart ventricle; motion; nuclear magnetic resonance imaging; pathophysiology; postoperative complication; procedures; prospective study; Adult; Diastole; Female; Heart Ventricles; Humans; Magnetic Resonance Imaging; Male; Motion; Postoperative Complications; Prospective Studies; Tetralogy of Fallot; Ventricular Dysfunction, Left; Young Adult |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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